Results 81 to 90 of about 46,417 (263)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Review of Accuracy Assessment Methods for Current Transformers: Errors, Uncertainties, and Dynamic Performance

Energies
Accurate electric current measurement is fundamental to the safe and efficient operation of modern power systems. Current transformers (CTs), which serve as a critical interface between high-voltage power networks and measuring or protection devices, are
Krzysztof Tomczyk, Marek Sieja, Ksenia Ostrowska, Danuta Owczarek   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Dynamic Differential Protection of Transformer Considering CT Saturation Based on Waveform Distortion Estimation

IEEE Access
The protection relay performs a significant role in maintaining the power system’s reliability and stability. However, Current Transformer (CT) saturation affects the overcurrent, differential and distance protection under various conditions ...
Nilesh Chothani, Swapnil Kumar
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Abnormal handling mechanism and improvement measures of optical DC current transformer in smart grid environment. [PDF]

PeerJ Comput Sci, 2022
Zhou S, Tang H, Pan B, Zhang W.
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Analysis of relay protection action of grounding fault of no-load charging of a 330 kV transformer

Gong-kuang zidonghua, 2013
In view of problem that a 330 kV start-up standby transformer took place relay protection action in no-load charging, the paper indicated that the action was caused by grounding fault of A-phase current transformer through analyzing charging current ...
LYU Bin, NI Sai-sai, LIU Yang, ZHONG Li-na   +3 more
doaj  

Detection failure elements in digital relay protection using the example of differential logic protection and the possibility of adaptive protection

Известия высших учебных заведений: Проблемы энергетики
Relevance. The efficiency and reliability of the relay protection system is influenced by many factors, such as: failure of the power switch, malfunction of the relay protection device components, errors in the operation of the current measurement, etc ...
M. V. Sharygin, Ahmed Sahib Naji Jeryo, Ammar Mousa Abdulhasan Alshaheri   +2 more
doaj   +1 more source

Dual beam-current transformer design for monitoring and reporting of electron ultra-high dose rate (FLASH) beam parameters. [PDF]

J Appl Clin Med Phys, 2023
Liu K, Palmiero A, Chopra N, Velasquez B, Li Z, Beddar S, Schüler E.   +6 more
europepmc   +1 more source