Results 51 to 60 of about 1,889,331 (297)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Research needs for Chagas disease prevention.
, 2010 We present an overview of the two main strategies for the primary (vector control) and secondary (patient care) prevention of Chagas disease (CD). We identify major advances, knowledge gaps, and key research needs in both areas.
Abad-Franch, Fernando +2 more
core +1 more source
Direct predictive current-error vector control for a direct matrix converter [PDF]
, 2018 This paper proposes a novel control strategy for matrix converters which is coined “Direct Predictive Current-error Vector Control”. The proposed control method retains the advantageous features of both a modulation scheme and of a predictive based ...
De Lillo, Liliana +3 more
core +2 more sources
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Current vector control challenges in the fight against malaria in Brazil
Revista da Sociedade Brasileira de Medicina Tropical, 2019 In Brazil, malaria is an important public health problem first reported in 1560. Historically, fluctuations in malaria cases in Brazil are attributed to waves of economic development; construction of railroads, highways, and hydroelectric dams; and ...
Djane Clarys Baia-da-Silva +12 more
doaj +1 more source
An estimate for the thermal photon rate from lattice QCD
, 2017 We estimate the production rate of photons by the quark-gluon plasma in lattice QCD. We propose a new correlation function which provides better control over the systematic uncertainty in estimating the photon production rate at photon momenta in the ...
Brandt, Bastian B. +4 more
core +1 more source
How much vector control is needed to achieve malaria elimination? [PDF]
, 2013 Roll Back Malaria's ambitious goals for global malaria reduction by 2015 represent a dilemma for National Malaria Control Programs (NMCPs) that are still far from malaria elimination.
Alimi, Temitope O. +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A fuzzy logic controller to line starting performance synchronous motor for a crane system using vector control [PDF]
, 2016 This paper presents the design process of a synchronous motor of crane system using vector control of line starting [1]. The preliminary design is d-q model armature rotor line start synchronous motor with vector control for decreasing a starting current
Ahmad, R. +3 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source