Results 41 to 50 of about 61,765 (256)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Assessing the influence of multimedia instruction on knowledge transfer in higher education: Multimodal learning experiences

Indonesian Journal of Education and Pedagogy
This study investigates the impact of multimedia instruction on knowledge transfer in higher education. Focused on the evolution from traditional lecture-based methods to interactive approaches, the research conducted at the Indonesian International ...
Daigo Bernadetha Haule, Thanaa Shaker, Godfrey Yohanes Nkwera   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Integrating Domestic Violence Education into the Pharmacy Curriculum

Pharmacy
Domestic violence (DV) is a pervasive issue with significant implications for public health, yet it remains under-addressed in healthcare systems.
Harjit K. Khera, Rita Wardan, Hiu Tek Wu, Andy Ling, Suzanne M. Caliph   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Impact of generative AI in medical education in India: a systematic review

Frontiers in Artificial Intelligence
BackgroundThe advent of generative Artificial Intelligence (AI) has presented a fundamental change in the approach to medical education across the world. In India, where the medical education is facing a shortage in faculties and resources, generative AI
Azfar Mateen, Visesh Kumar, Ajay Kumar Singh, Berendra Yadav, Mala Mahto, Atiq Hassan, Nazim Nasir   +6 more
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Integrating Computation into the Physics Curriculum [PDF]

, 2001
Some of the challenges of incorporating computational methods into the physics curriculum are discussed. These challenges include teaching the methods of computational physics in the same spirit as we presently teach mathematics, changing the curriculum to reflect the new ways of thinking that have arisen due to the use of computer technology, and ...
Harvey Gould, Jan Tobochnik
openaire   +2 more sources

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Mainstreaming climate change in school curricula: critical review of pedagogy, policy and Global South perspectives

Cogent Education
This study examines the integration of climate change into school curricula worldwide, focusing on practical pedagogical approaches and contrasting those of the Global South and Global North.
Joy Nneamaka Obi, Emmanuel Ojo
doaj   +1 more source