Results 101 to 110 of about 261,861 (299)
, 2020 Preference for curved over sharp-angled contours is a well-known effect. However, it was quite unexplored during the 20th century and only a few sporadic studies dealt with it. Nevertheless, there has been renewed interest in this topic over the past two decades.
Guido Corradi, Enric Munar
openaire +3 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Clinical Remarks on the Treatment of Angular Curvature of the Spine [PDF]
, 1887 R. Davy
openalex +1 more source
CFD study of some factors affecting performance of HAWT with swept blades
International Journal of Sustainable Energy, 2017 Most modern high-power wind turbines are horizontal axis type with straight twisted blades. Upgrading power and performance of these turbines is considered a challenge.
M.G. Khalafallah, A.M. Ahmed, M.K. Emam
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Treatment of Angular Curvature of the Spine by a Plaster of Paris Jacket Applied in the Recumbent Posture [PDF]
, 1879 Thomas James Walker
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Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source