Results 101 to 110 of about 267,369 (299)
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Superintegrability on Three-Dimensional Riemannian and Relativistic Spaces of Constant Curvature
Symmetry, Integrability and Geometry: Methods and Applications, 2006 A family of classical superintegrable Hamiltonians, depending on an arbitrary radial function, which are defined on the 3D spherical, Euclidean and hyperbolic spaces as well as on the (2+1)D anti-de Sitter, Minkowskian and de Sitter spacetimes is ...
Francisco José Herranz +1 more
doaj
Curvature and Bending Constants for Phosphatidylserine-Containing Membranes [PDF]
, 2003 Nola Fuller +2 more
openalex +1 more source
Nonnegative Curvature on Piecewise Constant Curvature Spaces [PDF]
Transactions of the American Mathematical Society, 1992 We consider piecewise flat and piecewise spherical spaces. We prove that every piecewise flat cobordism which is a product near the boundary and has nonnegative curvature must be trivial in the metric sense. We also obtain several restrictions for piecewise p p -spherical manifolds with nonnegative curvature and diameter equal to
openaire +2 more sources
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
3D simulations of pillar formation around HII regions: the importance of shock curvature [PDF]
, 2011 P. Tremblin +7 more
openalex +1 more source
Erratum to: Total Scalar Curvature and Harmonic Curvature
Taiwanese Journal of Mathematics, 2016 It has been realized that the proof of Theorem 5.1 in Section 5 is imcomplete. It was pointed out by Professor Jongsu Kim and Israel Evangelista.
Yun, Gabjin +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Gravitational effective action at second order in curvature and gravitational waves [PDF]
, 2017 Xavier Calmet +2 more
openalex +1 more source