Results 121 to 130 of about 267,369 (299)
Plastic rotation and tension stiffening effect analysis in beams using photogrammetry
Revista IBRACON de Estruturas e MateriaisInnovative procedures for monitoring experimental tests using photogrammetry and image processing have been recently proposed. This manuscript aims at providing a practical demonstration of the advantages of using these new techniques in experimental ...
R. N. F. do Carmo +2 more
doaj +1 more source
Non-perturbative effects of primordial curvature perturbations on the apparent value of a cosmological constant [PDF]
, 2014 Antonio Enea Romano +7 more
openalex +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Imprints of Intrinsic and Exterior Curvatures in Cosmology [PDF]
, 2021 Ali A. Asgari +3 more
openalex +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Curvature properties of novel forms of phosphatidylcholine with branched acyl chains [PDF]
, 2000 Richard M. Epand +3 more
openalex +1 more source
On the semicontinuity of curvatures
Commentarii Mathematici Helvetici, 1992 For a convex body \(K\) in \(\mathbb{R}^ n\) with a boundary of class \(C^ 2\) and positive curvatures and for \(\alpha\in\mathbb{R}\backslash\{0\}\) and \(j=1,\ldots,n-1\), let \[ \psi^ \alpha_ j(K)=\left\{{1\over\omega_ n}\int_{S^{n-1}}s_ j(K,u)^ \alpha d\omega(u)\right\}^{1/\alpha}, \] where \(s_ j(K,u)\) is the normalized \(j\)-th elementary ...
openaire +2 more sources
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source