Results 71 to 80 of about 261,861 (299)

Analysis of Geometric Properties of Ternary Four-Point Rational Interpolating Subdivision Scheme

Mathematics, 2020
Shape preservation has been the heart of subdivision schemes (SSs) almost from its origin, and several analyses of SSs have been established. Shape preservation properties are commonly used in SSs and various ways have been discovered to connect smooth ...
Pakeeza Ashraf, Bushra Nawaz, Dumitru Baleanu, Kottakkaran Sooppy Nisar, Abdul Ghaffar, Muhammad Aqeel Ahmed Khan, Saima Akram   +6 more
doaj   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Sensory prediction on a whiskered robot: A tactile analogy to "optic flow"

Frontiers in Neurorobotics, 2012
When an animal moves an array of sensors (e.g., the hand, the eye) through the environment, spatial and temporal gradients of sensory data are related by the velocity of the moving sensory array.
Christopher L Schroeder, Mitra J Z Hartmann, Mitra J Z Hartmann   +2 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Yang-Mills equations on conformally connected torsion-free 4-manifolds with different signatures

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2017
In this paper we study spaces of conformal torsion-free connection of dimension 4 whose connection matrix satisfies the Yang-Mills equations. Here we generalize and strengthen the results obtained by us in previous articles, where the angular metric of ...
Leonid N Krivonosov, Vyacheslav A Luk’yanov   +1 more
doaj   +1 more source

The Bourguignon Laplacian and Harmonic Symmetric Bilinear Forms

Mathematics, 2020
In this paper, we study the kernel and spectral properties of the Bourguignon Laplacian on a closed Riemannian manifold, which acts on the space of symmetric bilinear forms (considered as one-forms with values in the cotangent bundle of this manifold ...
Vladimir Rovenski, Sergey Stepanov, Irina Tsyganok   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evaluation and zoning of soil erosion potential using geomorphometric indexes and Fuzzy approach in Khiavchai watershed, Meshginshahr [PDF]

مطالعات جغرافیایی مناطق خشک
Aim: Erosion is a critical geomorphological process with significant environmental implications, including land degradation, fertility loss, and negative effects on aquatic ecosystems.
Faraiba Esfandyari Darabad, Mahya Yansori, Maryam Adhami, Raoof Mostafazadeh   +3 more
doaj   +1 more source

CCT4 promotes tunneling nanotube formation

FEBS Letters, EarlyView.
Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto, Akiko Asada, Taro Saito, Kanae Ando   +3 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source