Results 81 to 90 of about 270,582 (289)

Curvature

open access: yes
AbstractThe notion of curvature is central to differential geometry and its numerous applications. The aim of this chapter is to offer a first introduction to curvature. Our main point is to explore how curvature connects to algebraic geometry. We start out with plane curves, and we then turn to more general real algebraic varieties.
Paul Breiding   +2 more
  +4 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

An approximate solution for modes of curved optical fiber

open access: yesФизика волновых процессов и радиотехнические системы, 2019
The paper presents an approximate analytical solution in closed form for the mode of a weakly guiding circular optical fiber with an arbitrary profile of the refractive index.
V.A. Burdin   +2 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Superintegrability on Three-Dimensional Riemannian and Relativistic Spaces of Constant Curvature

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2006
A family of classical superintegrable Hamiltonians, depending on an arbitrary radial function, which are defined on the 3D spherical, Euclidean and hyperbolic spaces as well as on the (2+1)D anti-de Sitter, Minkowskian and de Sitter spacetimes is ...
Francisco José Herranz   +1 more
doaj  

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