Results 81 to 90 of about 1,081,533 (280)
Automatic Bayesian Curve Fitting
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1998 Summary A method of estimating a variety of curves by a sequence of piecewise polynomials is proposed, motivated by a Bayesian model and an appropriate summary of the resulting posterior distribution. A joint distribution is set up over both the number and the position of the knots defining the piecewise polynomials.
Denison, D. G. T. +2 more
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Curve-Fitting for Bayesians? [PDF]
, 2015 Bayesians often assume, suppose, or conjecture that for any reasonable explication of the notion of simplicity a prior can be designed that will enforce a preference for hypotheses simpler in just that sense.
Belot, Gordon
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2010 We study the string tension as a function of temperature, fitting the SU(3) lattice QCD finite temperature free energy potentials computed by the Bielefeld group.
A. Fetter +4 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
THEMIS signal analysis statistics research program - Development and analysis of modified paired comparisons by use of linearized nonlinear regression [PDF]
Curve fitting for modified paired comparisons using linearized nonlinear ...
Walsh, J. E.
core +1 more source
Curve fitting with the Bubble Board [PDF]
, 2012 The bubble board is a device to create simultaneously 56 identical soap bubbles. Students study the relation between time and the number of remaining bubbles for different concentrations of glycerin and use linear, exponential, and logistic decay ...
Biehl, L. Charles +3 more
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Piecewise cubic curve-fitting algorithm [PDF]
Mathematics of Computation, 1987 We give a piecewise cubic curve fitting algorithm which preserves monotonicity of the data. The algorithm has a higher order of convergence than the Fritsch-Carlson algorithm and is simpler than the Eisenstat-Jackson-Lewis algorithm.
openaire +2 more sources