Results 101 to 110 of about 1,745,742 (268)
Engenharia Agrícola, 2013 The edafoclimatic conditions of the Brazilian semiarid region favor the water loss by surface runoff. The state of Ceará, almost completely covered by semiarid, has developed public policies for the construction of dams in order to attend the varied ...
Raimundo A. de O. Leão +3 more
doaj
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Curves with a prescribed number of rational points
Finite Fields and Their Applications, 2011 Let \(q\) be a prime power. Let \(g\) and \(N\) be non-negative integers. Here a curve refers to an algebraic curve over \(\mathbb{F}_q\) which is smooth, projective and absolutely irreducible. The author introduces the interesting concept \[ \mathcal{G}(q,N):= \{ g\mid\text{there exists a curve over \(\mathbb{F}_q\) of genus \(g\) having exactly \(N\)
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Media Komunikasi Teknik SipilThe Aesesa watershed is the largest watershed in the Flores River Basin located in Ngada Regency and Nagekeo Regency, with a watershed area of 1,169.24 km2 and a main river length of 66.92 km.
Denik Sri Krisnayanti +3 more
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FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
, 2004 We generalize a theorem of D. Rohrlich concerning root numbers of elliptic curves over the field of rational numbers. Our result applies to curves of all higher genera over number fields. Namely, under certain conditions which naturally extend the conditions used by D.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Gradation of Algebras of Curves by the Winding Number
, 2017 Changed acknowledgments and Definition 2 ...
Bakhira, Mohamed Imad, Cooper, Benjamin
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