Results 121 to 130 of about 1,748,935 (267)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Water Discharge Peak Estimation Based on HEC‐HMS and Predicted Curve Numbers for Flood Forecast in the River Brembo (Northern Italy)

Journal of Flood Risk Management
This paper proposes a novel methodology for peak flow estimation. This methodology uses single‐event hydrological modeling based on the software HEC‐HMS and curve numbers (CNs) estimated as a function of antecedent and current weather variables and is ...
Carlo Giudicianni, Hossein Aghaee, Luca Ventura, Enrico Creaco   +3 more
doaj   +1 more source

Author Correction: HYSOGs250m, global gridded hydrologic soil groups for curve-number-based runoff modeling. [PDF]

Sci Data, 2019
Ross CW, Prihodko L, Anchang J, Kumar S, Ji W, Hanan NP.   +5 more
europepmc   +1 more source

A bound on the number of points of a plane curve

Finite Fields and Their Applications, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

HYSOGs250m, global gridded hydrologic soil groups for curve-number-based runoff modeling. [PDF]

Sci Data, 2018
Ross CW, Prihodko L, Anchang J, Kumar S, Ji W, Hanan NP.   +5 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Physics attributed to curve number model illustrate need for caution, and ecological responses often lag restoration efforts. [PDF]

Proc Natl Acad Sci U S A, 2014
Moglen GE, Palmer MA.
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Wildfire‐Induced Enhancement in Downstream Flood Discharge in Watersheds of California

Journal of Flood Risk Management
Global climate change is increasingly associated with the prevalence of extreme precipitation and large wildfires. The influence of large wildfires on downstream flood discharge is concerning, particularly from a flood risk management perspective, where ...
Wasitha Dilshan, Yusuke Hiraga, So Kazama   +2 more
doaj   +1 more source