Results 131 to 140 of about 11,657,940 (311)
Curves with a prescribed number of rational points
Finite Fields and Their Applications, 2011 Let \(q\) be a prime power. Let \(g\) and \(N\) be non-negative integers. Here a curve refers to an algebraic curve over \(\mathbb{F}_q\) which is smooth, projective and absolutely irreducible. The author introduces the interesting concept \[ \mathcal{G}(q,N):= \{ g\mid\text{there exists a curve over \(\mathbb{F}_q\) of genus \(g\) having exactly \(N\)
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
, 2004 We generalize a theorem of D. Rohrlich concerning root numbers of elliptic curves over the field of rational numbers. Our result applies to curves of all higher genera over number fields. Namely, under certain conditions which naturally extend the conditions used by D.
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How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Reconciling wage curve and Phillips curve
, 2005 The wage curve is the negative relationship that links wage levels to the unemployment rate. It fits accurately with modern non-competitive labour-market models, but goes against a Phillips-curve modelling, because the latter ties wage growth to the ...
Montuenga-Gómez, V.M. +1 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
ROC curve on number of VEBs and major cardiac events.
, 2016 ROC curve on number of VEBs and major cardiac events (considered as sudden cardiac death or ICD implantation).
Silvia Laura Bosello (204811) +10 more
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Assessment of SCS-CN Model in Runoff Estimation Case Study: Amir-Kabir (Karaj) Dam Watershed [PDF]
جغرافیا و توسعه, 2006 maniegeh Ghohroudi Tali
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source