Results 111 to 120 of about 11,657,940 (311)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

θ-congruent numbers and elliptic curves [PDF]

open access: yesActa Arithmetica, 2000
Let \(\Theta\) be a real number with ...
openaire   +2 more sources

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Application of NRCS-CN method for estimation of watershed runoff and disaster risk

open access: yesGeomatics, Natural Hazards & Risk, 2019
The NRCS-CN method is widely applied in the estimation of precipitation runoff. It primarily relies on soil mapping and land use data as input parameters, although land use data is not frequently updated.
Wen-Yan Zhang
doaj   +1 more source

Evaluation of flood determination with various methods: Case study of Ayamama Creek

open access: yesDoğal Afetler ve Çevre Dergisi, 2017
In many developing countries, rapid urbanization, disaster risks and affectability pose a great problem. Uncontrolled developments will bring out the inherent risks related with high-density environments and inadequate infrastructure. Advances in mapping
Orkan Özcan
doaj   +1 more source

The Wage Curve Reloaded [PDF]

open access: yes
This paper provides evidence for the existence of a wage curve -- a micro-econometric association between the level of pay and the local unemployment rate -- in modern U.S. data. Consistent with recent evidence from more than 40 other countries, the wage
David G. Blanchflower, Andrew J. Oswald
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Water Discharge Peak Estimation Based on HEC‐HMS and Predicted Curve Numbers for Flood Forecast in the River Brembo (Northern Italy)

open access: yesJournal of Flood Risk Management
This paper proposes a novel methodology for peak flow estimation. This methodology uses single‐event hydrological modeling based on the software HEC‐HMS and curve numbers (CNs) estimated as a function of antecedent and current weather variables and is ...
Carlo Giudicianni   +3 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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