Results 101 to 110 of about 2,111,624 (316)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Curves related to Coulter's maximal curves
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Emrah Çakçak, Ferruh Özbudak
openaire +2 more sources
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
On maximal curves that are not quotients of the Hermitian curve
For each prime power $\ell$ the plane curve $\mathcal X_\ell$ with equation $Y^{\ell^2-\ell+1}=X^{\ell^2}-X$ is maximal over $\mathbb{F}_{\ell^6}$. Garcia and Stichtenoth in 2006 proved that $\mathcal X_3$ is not Galois covered by the Hermitian curve and raised the same question for $\mathcal X_\ell$ with $\ell>3$; in this paper we show that ...
Massimo Giulietti +2 more
openaire +3 more sources
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Families of elliptic curves with rational 3-torsion
In this paper we look at three families of elliptic curves with rational 3-torsion over a finite field. These families include Hessian curves, twisted Hessian curves, and a new family we call generalized DIK curves. We find the number of -isogeny classes
Moody Dustin, Wu Hongfeng
doaj +1 more source
Heights on elliptic curves over number fields, period lattices, and complex elliptic logarithms [PDF]
This thesis presents some major improvements in the following computations: a lower bound for the canonical height, period lattices, and elliptic logarithms.
Thongjunthug, Thotsaphon
core
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source

