Results 101 to 110 of about 2,111,624 (316)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Curves related to Coulter's maximal curves

open access: yesFinite Fields and Their Applications, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Emrah Çakçak, Ferruh Özbudak
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

On maximal curves that are not quotients of the Hermitian curve

open access: yesFinite Fields and Their Applications, 2016
For each prime power $\ell$ the plane curve $\mathcal X_\ell$ with equation $Y^{\ell^2-\ell+1}=X^{\ell^2}-X$ is maximal over $\mathbb{F}_{\ell^6}$. Garcia and Stichtenoth in 2006 proved that $\mathcal X_3$ is not Galois covered by the Hermitian curve and raised the same question for $\mathcal X_\ell$ with $\ell>3$; in this paper we show that ...
Massimo Giulietti   +2 more
openaire   +3 more sources

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Families of elliptic curves with rational 3-torsion

open access: yesJournal of Mathematical Cryptology, 2012
In this paper we look at three families of elliptic curves with rational 3-torsion over a finite field. These families include Hessian curves, twisted Hessian curves, and a new family we call generalized DIK curves. We find the number of -isogeny classes
Moody Dustin, Wu Hongfeng
doaj   +1 more source

Heights on elliptic curves over number fields, period lattices, and complex elliptic logarithms [PDF]

open access: yes
This thesis presents some major improvements in the following computations: a lower bound for the canonical height, period lattices, and elliptic logarithms.
Thongjunthug, Thotsaphon
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy