Results 121 to 130 of about 2,111,624 (316)
International Journal of Mathematics and Mathematical Sciences, 2006 Let kq denote the finite field of order q and odd characteristic p. For a∈kq, let gd(x,a) denote the Dickson polynomial of degree d defined by gd(x,a)=∑i=0[d/2]d/(d−i)(d−ii)(−a)ixd−2i.
Javier Gomez-Calderon
doaj +1 more source
Equivariant Riemann-Roch theorems for curves over perfect fields
, 2008 We prove an equivariant Riemann-Roch formula for divisors on algebraic curves over perfect fields. By reduction to the known case of curves over algebraically closed fields, we first show a preliminary formula with coefficients in Q.
Koeck, Bernhard +3 more
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
International Journal of Mathematics and Mathematical Sciences, 2002 We discuss the dynamics of the correspondences associated to those plane curves whose local sections contract the Poincaré metric in a hyperbolic planar domain.
Araceli Bonifant, Marius Dabija
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A large number of functional forms have been suggested in the literature for estimating Lorenz curves that describe the relationship between income and population shares.
Duangkamon Chotikapanich +1 more
core
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Free curves, eigenschemes, and pencils of curves
Bulletin of the London Mathematical SocietyAbstractLet . A reduced plane curve is free if its associated module of tangent derivations is a free ‐module, or equivalently if the corresponding sheaf of vector fields tangent to splits as a direct sum of line bundles on . In general, free curves are difficult to find, and in this paper, we describe a new method for constructing free curves in .
Roberta Di Gennaro +4 more
openaire +4 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source