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Cushing's Pituitary Basophilism (Cushing's Disease) [PDF]
Philip Ellman
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Cushing's disease, or pituitary ACTH dependent Cushing's syndrome, is a rare disease responsible for increased morbidity and mortality. Signs and symptoms of hypercortisolism are usually non specific: obesity, signs of protein wasting, increased blood pressure, variable levels of hirsutism.
Isabelle Morange+3 more
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In patients with Cushing’s disease (CD), prompt diagnosis and treatment are essential for favorable long-term outcomes, although this remains a challenging task. The differential diagnosis of CD is still difficult in some patients, even with an organized stepwise diagnostic approach.
Shozo Yamada, Hiroshi Nishioka
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Cushing's disease and bone. [PDF]
AbstractBone impairment associated with Cushing’s disease (CD) is a complex disorder, mainly involving deterioration of bone quality and resulting in an increased fracture rate, often despite normal bone mineral density. Bone complications are common in patients with CD at the time of diagnosis but may persist even after successful treatment.
Zdrojowy-Wełna A+2 more
europepmc +3 more sources
Comorbidities in Cushing’s disease [PDF]
Cushing's disease is a rare disorder characterized by overproduction of ACTH from a pituitary adenoma leading to hypercortisolemia that in turn leads to increased morbidity and mortality.Here we review the comorbidities associated with Cushing's disease and their impact on quality of life and mortality.Recent evidence suggests that correction of ...
Susmeeta T. Sharma+2 more
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The Treatment of Cushing's Disease [PDF]
AbstractCushing's disease (CD), or pituitary-dependent Cushing's syndrome, is a severe endocrine disease caused by a corticotroph pituitary tumor and associated with increased morbidity and mortality. The first-line treatment for CD is pituitary surgery, which is followed by disease remission in around 78% and relapse in around 13% of patients during ...
PIVONELLO, ROSARIO+3 more
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Genetics of Cushing's disease [PDF]
SummaryCushing's disease (CD) is a rare disabling condition caused by Adrenocorticotropic hormone (ACTH)‐secreting adenomas of the pituitary. The majority of corticotropic adenomas are monoclonal and occur sporadically. Only rarely does CD arise in the context of genetic familial syndromes.
Adriana Albani+3 more
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Prevalência da hipertensão arterial na síndrome de Cushing.
To determine the prevalence of hypertension (HT) in patients with Cushing's syndrome.We studied 23 patients with Cushing's syndrome, 17 women (mean +/- SD age = 42.8 +/- 15.6 years) and 6 men (mean +/- SD age = 34.8 +/- 10.2 years).
D Rodrigues+5 more
doaj +1 more source
Ectopic Cushing’s syndrome (ECS) is a rare disease associated with significant comorbidity. Among the causes of Cushing's syndrome, adrenocorticotropic hormone-producing extrapituitary tumours are rarely reported.
Laura González Fernández+9 more
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