Results 231 to 240 of about 12,049 (277)
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Best Practice & Research Clinical Endocrinology & Metabolism, 2009
Cushing's syndrome refers to the clinical manifestations induced by chronic exposure to excess glucocorticoids. There are three pathological conditions that can result in the chronic overproduction of endogenous cortisol in man: the most frequent is Cushing's disease where adrenocorticotropic hormone (ACTH) is overproduced by a pituitary corticotroph ...
Lionel Groussin +3 more
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Cushing's syndrome refers to the clinical manifestations induced by chronic exposure to excess glucocorticoids. There are three pathological conditions that can result in the chronic overproduction of endogenous cortisol in man: the most frequent is Cushing's disease where adrenocorticotropic hormone (ACTH) is overproduced by a pituitary corticotroph ...
Lionel Groussin +3 more
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2008
Cushing's disease is a form of Cushing's syndrome, persistent inappropriate hypercortisolism, that results from pituitary ACTH hypersecretion. It currently accounts for 70 per cent of adult cases of Cushing's syndrome and affects mainly women of childbearing age.
James W. Findling +2 more
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Cushing's disease is a form of Cushing's syndrome, persistent inappropriate hypercortisolism, that results from pituitary ACTH hypersecretion. It currently accounts for 70 per cent of adult cases of Cushing's syndrome and affects mainly women of childbearing age.
James W. Findling +2 more
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Current Diabetes Reports, 2017
This review focuses on the pathophysiological and clinical aspects of diabetes mellitus occurring in patients with Cushing disease (CD).Insulin resistance and impairment in insulin secretion are both involved in the pathogenesis of glucocorticoid-induced diabetes.
Mazziotti, G. +5 more
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This review focuses on the pathophysiological and clinical aspects of diabetes mellitus occurring in patients with Cushing disease (CD).Insulin resistance and impairment in insulin secretion are both involved in the pathogenesis of glucocorticoid-induced diabetes.
Mazziotti, G. +5 more
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Harvey Cushing: Cushing's Disease
Journal of Perioperative Practice, 2012In 1932 Harvey Cushing published an article entitled ‘Basophil adenomas of the pituitary and their clinical manifestations'. These are rare tumours of the anterior pituitary gland, at the base of the brain, with striking manifestations, which include adiposity of the face and trunk, but not the limbs, weakness, fatigue, abdominal striae, facial hair ...
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Nature Reviews Endocrinology, 2011
Cushing disease is caused by a corticotroph tumor of the pituitary gland. Patients with Cushing disease are usually treated with transsphenoidal surgery, as this approach leads to remission in 70-90% of cases and is associated with low morbidity when performed by experienced pituitary gland surgeons.
Brooke Swearingen +2 more
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Cushing disease is caused by a corticotroph tumor of the pituitary gland. Patients with Cushing disease are usually treated with transsphenoidal surgery, as this approach leads to remission in 70-90% of cases and is associated with low morbidity when performed by experienced pituitary gland surgeons.
Brooke Swearingen +2 more
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Diagnosis of Cushing’s disease
Pituitary, 2015Diagnosis of Cushing's disease frequently remains a challenge. In this review we critically appraise the clinical features, biochemical tests, and imaging modalities used for this purpose. We outline recommendations for approaches to clinical investigation, with a particular focus on developments made within the last two years.
John Newell-Price, Eleni Daniel
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The American Journal of Surgery, 1979
Harvey Cushing [I] presented and subsequently published his extraordinary study of basophilic pituitary adenomas in 1932. Validation of these observations followed long after his death through the fortunate coincidence of two developments: first, conclusive biochemical definition of pituitary-based hypercortisolism, for the first time differentiating ...
Charles B. Wilson +2 more
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Harvey Cushing [I] presented and subsequently published his extraordinary study of basophilic pituitary adenomas in 1932. Validation of these observations followed long after his death through the fortunate coincidence of two developments: first, conclusive biochemical definition of pituitary-based hypercortisolism, for the first time differentiating ...
Charles B. Wilson +2 more
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2003
Cushing’s syndrome (CS) results from prolonged exposure of tissues to excess of glucocorticoids. After Harvey Cushing’ s initial report in the early 20th century (1), CS has been etiologically subdivided into adenocorticotropin hormone (ACTH)-independent (nonpituitary) or ACTH-dependent (2–4).
George P. Chrousos, Christian A Koch
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Cushing’s syndrome (CS) results from prolonged exposure of tissues to excess of glucocorticoids. After Harvey Cushing’ s initial report in the early 20th century (1), CS has been etiologically subdivided into adenocorticotropin hormone (ACTH)-independent (nonpituitary) or ACTH-dependent (2–4).
George P. Chrousos, Christian A Koch
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Intermittent Cushing's disease
The American Journal of Medicine, 1979Described here is a young woman with intermittent Cushing's disease associated with psychotic disturbance. On five occasions, over a period of four years, she became severely depressed and had acne, amenorrhea, hirsuties and moon facies. On each of the first four occasions the symptoms lasted from two to three months and disappeared spontaneously ...
Christopher J. Burke +3 more
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Archives of Internal Medicine, 1985
Cushing's syndrome continues to tax the most discerning clinician. I review pituitary-dependent adrenal hyperplasia (Cushing's disease), including recent experiences with Cushing's disease at Duke University, Durham, NC, and relate these observations to the current ideas as to pathophysiology, etiology, and management of Cushing's disease ...
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Cushing's syndrome continues to tax the most discerning clinician. I review pituitary-dependent adrenal hyperplasia (Cushing's disease), including recent experiences with Cushing's disease at Duke University, Durham, NC, and relate these observations to the current ideas as to pathophysiology, etiology, and management of Cushing's disease ...
openaire +3 more sources