Results 241 to 250 of about 12,049 (277)
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American Journal of Medical Genetics, 1981
AbstractA 28‐year‐old woman and her niece presented with manifestations of the Cushing syndrome. Endocrine studies, including small‐ and large‐dose dexamethasone‐suppression tests confirmed the diagnosis of pituitary ACTH excess. The first patient had a sella of normal size and went into clinical and hormonal remission after external pituitary ...
John M. Opitz +2 more
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AbstractA 28‐year‐old woman and her niece presented with manifestations of the Cushing syndrome. Endocrine studies, including small‐ and large‐dose dexamethasone‐suppression tests confirmed the diagnosis of pituitary ACTH excess. The first patient had a sella of normal size and went into clinical and hormonal remission after external pituitary ...
John M. Opitz +2 more
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Endocrinology and Metabolism Clinics of North America, 1994
As with adults, the diagnosis of Cushing's disease in childhood can be difficult. The clinical presentation in children is distinctive in terms of the effects on growth and pubertal development. The biochemical diagnosis can usually be made with standard dexamethasone suppression testing, similar to such testing in adults.
Donnald Zimmerman, Matthew C. Leinung
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As with adults, the diagnosis of Cushing's disease in childhood can be difficult. The clinical presentation in children is distinctive in terms of the effects on growth and pubertal development. The biochemical diagnosis can usually be made with standard dexamethasone suppression testing, similar to such testing in adults.
Donnald Zimmerman, Matthew C. Leinung
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New England Journal of Medicine, 1955
IN his classic monograph on the pituitary gland published in 1912 Harvey Cushing1 described the case of a young woman with a disorder that has come to bear his name. The patient suffered from headaches and backache. She was obese about the head, neck and trunk, but her extremities were thin.
Oliver Cope, John W. Raker
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IN his classic monograph on the pituitary gland published in 1912 Harvey Cushing1 described the case of a young woman with a disorder that has come to bear his name. The patient suffered from headaches and backache. She was obese about the head, neck and trunk, but her extremities were thin.
Oliver Cope, John W. Raker
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Equine Cushing's disease [PDF]
Veterinary Clinics of North America: Equine Practice, 2002 Equine Cushing's disease (ECD) is a chronic progressive disease of the intermediate pituitary gland of older horses. Horses with Cushing's disease often have other health problems, such as laminitis, chronic infections, pseudolactation, and other issues. Diagnosis of ECD is usually based on clinical signs and endocrine tests.
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Endocrinología y Nutrición (English Edition), 2014
The aim of this study was to review the literature published and the most important papers presented to meetings on Cushing's disease from October 2011 to September 2012. The selection has been performed according to the authors' criteria. Articles have been classified into five groups: quality of life and perception of the disease, clinical features ...
Ana Chacón Oreja +3 more
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The aim of this study was to review the literature published and the most important papers presented to meetings on Cushing's disease from October 2011 to September 2012. The selection has been performed according to the authors' criteria. Articles have been classified into five groups: quality of life and perception of the disease, clinical features ...
Ana Chacón Oreja +3 more
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The Lancet, 2005
A 10-year-old twin girl presented elsewhere with weight gain and growth retardation. At age 14 years she was diagnosed with Cushing’s disease, and transsphenoidal pituitary tumour resection was attempted without improvement. She presented to the National Institutes of Health at age 15 years with cerebral MRI showing persistent tumour.
Joshua G. Kouri, Edward H. Oldfield
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A 10-year-old twin girl presented elsewhere with weight gain and growth retardation. At age 14 years she was diagnosed with Cushing’s disease, and transsphenoidal pituitary tumour resection was attempted without improvement. She presented to the National Institutes of Health at age 15 years with cerebral MRI showing persistent tumour.
Joshua G. Kouri, Edward H. Oldfield
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The pathology of cushing's disease
The Journal of Steroid Biochemistry and Molecular Biology, 1993In this brief review the pathology of Cushing's disease is summarized. The most frequent morphologic abnormality is a basophilic microadenoma of the pituitary accompanied by the Crooke's hyaline change in the cytoplasm of nontumorous corticotrophs.
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Cushing's disease in childhood
Trends in Endocrinology & Metabolism, 1996Cushing's disease is rare in childhood. There is an equal sex incidence, and it accounts for approximately 75% of pediatric causes of Cushing's syndrome. Predominant features are weight gain, growth failure, virilization, and headache. Following confirmation of the presence of inappropriate hypercortisolemia, the accurate differential diagnosis to ...
Martin O. Savage, G. M. Besser
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1987
Cushing’s disease, or pituitary-dependent hypercortisolism, is an entity characterized by the development of hypercortisolism secondary to inappropriate ACTH secretion by the pituitary gland. Since the original description by Harvey Cushing in 1932,1there have been remarkable strides in our understanding of the pathophysiology, laboratory diagnosis and
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Cushing’s disease, or pituitary-dependent hypercortisolism, is an entity characterized by the development of hypercortisolism secondary to inappropriate ACTH secretion by the pituitary gland. Since the original description by Harvey Cushing in 1932,1there have been remarkable strides in our understanding of the pathophysiology, laboratory diagnosis and
openaire +2 more sources