Results 151 to 160 of about 6,492 (176)
Some of the next articles are maybe not open access.
The Indian Journal of Pediatrics, 1997
Endogenous Cushing's Syndrome (CS) is a relatively uncommon disease in children. The etiology is more often a primary adrenal cause in infants and younger children, and corticotroph adenoma in older ones. Diagnostic evaluation must be stepwise and methodical, aimed at first confirming the presence of the disease, and then looking for the etiology.
openaire +2 more sources
Endogenous Cushing's Syndrome (CS) is a relatively uncommon disease in children. The etiology is more often a primary adrenal cause in infants and younger children, and corticotroph adenoma in older ones. Diagnostic evaluation must be stepwise and methodical, aimed at first confirming the presence of the disease, and then looking for the etiology.
openaire +2 more sources
The Lancet, 2015
Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's syndrome, including debilitating morbidities and increased mortality. Genetic and molecular mechanisms responsible for excess cortisol secretion by primary adrenal lesions and adrenocorticotropic hormone (ACTH) secretion from corticotroph or ectopic tumours have ...
Lacroix, A +3 more
openaire +2 more sources
Chronic exposure to excess glucorticoids results in diverse manifestations of Cushing's syndrome, including debilitating morbidities and increased mortality. Genetic and molecular mechanisms responsible for excess cortisol secretion by primary adrenal lesions and adrenocorticotropic hormone (ACTH) secretion from corticotroph or ectopic tumours have ...
Lacroix, A +3 more
openaire +2 more sources
Nature Reviews Disease Primers
Cushing syndrome (CS) is a constellation of signs and symptoms caused by excessive exposure to exogenous or endogenous glucocorticoid hormones. Endogenous CS is caused by increased cortisol production by one or both adrenal glands (adrenal CS) or by elevated adrenocorticotropic hormone (ACTH) secretion from a pituitary tumour (Cushing disease (CD)) or ...
Lynnette K. Nieman +6 more
openaire +2 more sources
Cushing syndrome (CS) is a constellation of signs and symptoms caused by excessive exposure to exogenous or endogenous glucocorticoid hormones. Endogenous CS is caused by increased cortisol production by one or both adrenal glands (adrenal CS) or by elevated adrenocorticotropic hormone (ACTH) secretion from a pituitary tumour (Cushing disease (CD)) or ...
Lynnette K. Nieman +6 more
openaire +2 more sources
JAMA, 2023
ImportanceCushing syndrome is defined as a prolonged increase in plasma cortisol levels that is not due to a physiological etiology. Although the most frequent cause of Cushing syndrome is exogenous steroid use, the estimated incidence of Cushing syndrome due to endogenous overproduction of cortisol ranges from 2 to 8 per million people annually ...
Martin, Reincke, Maria, Fleseriu
openaire +2 more sources
ImportanceCushing syndrome is defined as a prolonged increase in plasma cortisol levels that is not due to a physiological etiology. Although the most frequent cause of Cushing syndrome is exogenous steroid use, the estimated incidence of Cushing syndrome due to endogenous overproduction of cortisol ranges from 2 to 8 per million people annually ...
Martin, Reincke, Maria, Fleseriu
openaire +2 more sources
New England Journal of Medicine, 1995
Cushing's syndrome is usually caused by the secretion of corticotropin or cortisol by a pituitary or adrenal tumor, respectively, or by ectopic secretion of corticotropin. It is possible to determine the specific abnormality in most patients, but it can sometimes be difficult to decide whether the patient has hypercortisolism and whether it is primary ...
openaire +2 more sources
Cushing's syndrome is usually caused by the secretion of corticotropin or cortisol by a pituitary or adrenal tumor, respectively, or by ectopic secretion of corticotropin. It is possible to determine the specific abnormality in most patients, but it can sometimes be difficult to decide whether the patient has hypercortisolism and whether it is primary ...
openaire +2 more sources
The Journal of Clinical Endocrinology & Metabolism, 1985
A woman with pituitary-dependent Cushing's disease remained hypercortisolemic after bilateral adrenalectomy. A search for an adrenal remnant by venous catheterization study suggested persistent cortisol-secreting tissue in the left adrenal bed. During ACTH stimulation, plasma corticosterone concentrations remained low and cortisol remained high ...
D M, Cook, A W, Meikle
openaire +2 more sources
A woman with pituitary-dependent Cushing's disease remained hypercortisolemic after bilateral adrenalectomy. A search for an adrenal remnant by venous catheterization study suggested persistent cortisol-secreting tissue in the left adrenal bed. During ACTH stimulation, plasma corticosterone concentrations remained low and cortisol remained high ...
D M, Cook, A W, Meikle
openaire +2 more sources
Journal of Surgical Oncology, 2012
AbstractCushing's syndrome (CS) results from prolonged exposure to elevated endogenous cortisol. Majority of cases are caused by ACTH, pituitary, or ectopic origin. Primary adrenal hypersecretion is 15–20% caused by adenomas, carcinomas (ACC), and rarely by nodular adrenocortical disease. CS presents with all typical features.
openaire +2 more sources
AbstractCushing's syndrome (CS) results from prolonged exposure to elevated endogenous cortisol. Majority of cases are caused by ACTH, pituitary, or ectopic origin. Primary adrenal hypersecretion is 15–20% caused by adenomas, carcinomas (ACC), and rarely by nodular adrenocortical disease. CS presents with all typical features.
openaire +2 more sources
The American Journal of Medicine, 1984
Cyclic Cushing's syndrome is a rare but increasingly recognized disorder of periodic fluctuations of adrenal steroid production. A case of cyclic Cushing's syndrome due to a pituitary adenoma is described. The patient demonstrated a prolonged cycle length of approximately six months, during which a spontaneous remission occurred both clinically and ...
R, Sakiyama +2 more
openaire +2 more sources
Cyclic Cushing's syndrome is a rare but increasingly recognized disorder of periodic fluctuations of adrenal steroid production. A case of cyclic Cushing's syndrome due to a pituitary adenoma is described. The patient demonstrated a prolonged cycle length of approximately six months, during which a spontaneous remission occurred both clinically and ...
R, Sakiyama +2 more
openaire +2 more sources
Acta Endocrinologica, 1978
ABSTRACT Cushing's syndrome has been demonstrated in four of seven siblings with clinical manifestations appearing around puberty in three of the four siblings. The only other associated findings in these cases were short stature and disturbed carbohydrate metabolism.
B, Arce, M, Licea, S, Hung, R, Padrón
openaire +2 more sources
ABSTRACT Cushing's syndrome has been demonstrated in four of seven siblings with clinical manifestations appearing around puberty in three of the four siblings. The only other associated findings in these cases were short stature and disturbed carbohydrate metabolism.
B, Arce, M, Licea, S, Hung, R, Padrón
openaire +2 more sources
Zentralblatt für Veterinärmedizin Reihe A, 2010
Summary This report deals with 21 dogs with spontaneous hyperadrenocorticism. The clinical picture was characterized by abdominal enlargement, polyphagia, polydipsia, muscular weakness, obesity and alopecia. Slight diabetes mellitus was encountered sporadically. In the bitches oestrus was usually absent for a long time.
A, Rijnberk +2 more
openaire +2 more sources
Summary This report deals with 21 dogs with spontaneous hyperadrenocorticism. The clinical picture was characterized by abdominal enlargement, polyphagia, polydipsia, muscular weakness, obesity and alopecia. Slight diabetes mellitus was encountered sporadically. In the bitches oestrus was usually absent for a long time.
A, Rijnberk +2 more
openaire +2 more sources