Complications of Cushing's syndrome: state of the art. [PDF]
The Lancet Diabetes and Endocrinology, 2016 Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive secretion of cortisol. The syndrome is associated with increased mortality and impaired quality of life because of the occurrence of comorbidities.
R. Pivonello +5 more
semanticscholar +3 more sources
Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma [PDF]
, 1985 Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a normal X-ray of the sella turcica.
Lüdecke, D. K. +2 more
core +4 more sources
Changes in adenosine 5'-monophosphate-activated protein kinase as a mechanism of visceral obesity in Cushing's syndrome [PDF]
, 2008 OBJECTIVE: Features of the metabolic syndrome such as central obesity with insulin resistance and dyslipidemia are typical signs of Cushing's syndrome and common side effects of prolonged glucocorticoid treatment.
Blerina Kola +31 more
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Medicine, 2005 Abstract Harvey Cushing described the first case of Cushing’s syndrome with a severe phenotype in 1912. Since that time, investigation and management of Cushing’s syndrome has remained a significant clinical challenge and patients suspected of this diagnosis warrant referral to major centres.
openaire +3 more sources
Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]
, 1989 We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
A Chatelain +19 more
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Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline.
Journal of Clinical Endocrinology and Metabolism, 2015 OBJECTIVE The objective is to formulate clinical practice guidelines for treating Cushing's syndrome. PARTICIPANTS Participants include an Endocrine Society-appointed Task Force of experts, a methodologist, and a medical writer.
L. Nieman +6 more
semanticscholar +1 more source
The effect of sodium valproate in Cushing's disease, Nelson's syndrome and Addison's disease [PDF]
, 1988 We investigated the effect of sodium valproate on plasma ACTH and serum cortisol concentrations in different pathological states of ACTH hypersecretion.
Allolio, B. +4 more
core +1 more source
Journal of Veterinary Internal Medicine, 2023 Background A prediction tool was developed and internally validated to aid the diagnosis of Cushing's syndrome in dogs attending UK primary‐care practices. External validation is an important part of model validation to assess model performance when used
Bart Eduardus Wilhelmus Ruijter +3 more
doaj +1 more source
Diagnosis and complications of Cushing's syndrome: a consensus statement.
Journal of Clinical Endocrinology and Metabolism, 2003 In October 2002, a workshop was held in Ancona, Italy, to reach a Consensus on the management of Cushing's syndrome. The workshop was organized by the University of Ancona and sponsored by the Pituitary Society, the European Neuroendocrine Association ...
G. Arnaldi +19 more
semanticscholar +1 more source
Nonhypnotic low-dose etomidate for rapid correction of hypercortisolaemia in cushing's syndrome [PDF]
, 1988 We determined the adrenostatic potential of low-dose nonhypnotic etomidate in six patients with Cushing's syndrome (ectopic Cushing's syndrome,n=2; Cushing's disease,n=3; bilateral adrenal adenoma,n=1). Etomidate was given as a continuous infusion for 32
Allolio, B. +5 more
core +1 more source