Results 11 to 20 of about 202,499 (369)
The Lancet, 2001 Cushing's syndrome results from lengthy and inappropriate exposure to excessive glucocorticoids. Untreated, it has significant morbidity and mortality. The syndrome remains a challenge to diagnose and manage. Here, we review the current understanding of pathogenesis, clinical features, diagnostic, and differential diagnostic approaches.
J. Newell-Price +3 more
semanticscholar +11 more sources
Journal of Clinical Medicine, 2019 In patients with Cushing’s disease (CD), prompt diagnosis and treatment are essential for favorable long-term outcomes, although this remains a challenging task. The differential diagnosis of CD is still difficult in some patients, even with an organized
Hiroshi Nishioka, S. Yamada
semanticscholar +3 more sources
Randomized Trial of Osilodrostat for the Treatment of Cushing Disease
Journal of Clinical Endocrinology and Metabolism, 2022 Context Cushing disease, a chronic hypercortisolism disorder, is associated with considerable morbidity and mortality. Normalizing cortisol production is the primary treatment goal.
M. Gadelha +15 more
semanticscholar +1 more source
Approach to the Patient: Diagnosis of Cushing Syndrome
Journal of Clinical Endocrinology and Metabolism, 2022 Cushing syndrome results from supraphysiological exposure to glucocorticoids and is associated with significant morbidity and mortality. The pathogenesis includes administration of corticosteroids (exogenous Cushing syndrome) or autonomous cortisol ...
M. Savas +4 more
semanticscholar +1 more source
Journal of neuroendocrinology, 2022 In the context of ACTH‐dependent Cushing's syndrome, ectopic ACTH secretion from a neuroendocrine tumour is not uncommon, and needs to be carefully differentiated from pituitary‐dependent Cushing's syndrome, Cushing's disease, in order to optimise ...
A. Hayes, A. Grossman
semanticscholar +1 more source
Librarians as methodological peer reviewers for systematic reviews: results of an online survey
Research Integrity and Peer Review, 2019 Background Developing a comprehensive, reproducible literature search is the basis for a high-quality systematic review (SR). Librarians and information professionals, as expert searchers, can improve the quality of systematic review searches ...
Holly K. Grossetta Nardini +7 more
doaj +1 more source
Valores hematológicos y bioquímicos en caninos con Hiperadrenocorticismo
Revista Científica, 2022 Con el objetivo de caracterizar el cuadro clínico en perros sospechosos de hiperadrenocorticismo (HAC) se llevó a cabo un estudio en la clínica veterinaria Mundo Animal de la ciudad de Puyo, Ecuador. Fueron seleccionados 23 pacientes que presentaron más
Carlos Andrés Guevara-Inga +1 more
doaj +1 more source
Interpretation of Consensus on Diagnosis and Management of Cushing's Disease: a Guideline Update from the Pituitary Society——Medical Therapies [PDF]
Zhongguo quanke yixue, 2022 Cushing's disease, the most common cause of endogenous Cushing's syndrome, is hypercortisolemia caused by adrenocorticotropic hormone-secreting pituitary adenoma.
TANG Yu, TAN Huiwen, LI Jianwei, YU Yerong
doaj +1 more source
BMC Neurology, 2017 Background Although International Classification of Disease, Ninth Revision, Clinical Modification (ICD9-CM) coding is the basis of administrative claims data, no study has validated an ICD9-CM algorithm to identify patients undergoing decompressive ...
Hormuzdiyar H. Dasenbrock +5 more
doaj +1 more source
The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline.
Journal of Clinical Endocrinology and Metabolism, 2008 OBJECTIVE The objective of the study was to develop clinical practice guidelines for the diagnosis of Cushing's syndrome. PARTICIPANTS The Task Force included a chair, selected by the Clinical Guidelines Subcommittee (CGS) of The Endocrine Society ...
L. Nieman +6 more
semanticscholar +1 more source