Results 91 to 100 of about 16,280 (231)

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Cardiovascular profile of Cushing Syndrome in mice [PDF]

Cushing Syndrome, reflecting endogenous overproduction of ACTH or exogenous exposure to glucocorticoid medication, increases cardiovascular risk. Hypertension is a major factor but underlying mechanisms are not clearly defined.
Krilis, Georgios, Jones, Natalie, Livingstone, Dawn, Costello, Hannah, Dhaun, Neeraj, Grenier, Celine, Stewart, Kevin, Bailey, Matthew, Ivy, Jessica   +8 more
core   +1 more source

Importance of Hypercortisolism in BP Control, Cardiovascular Risk and in Patients With Difficult‐to‐Control Hypertension: An Overview for Primary Care Physicians

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Hypertension remains one of the most prevalent and consequential modifiable cardiovascular risk factors worldwide, affecting approximately 1.28 billion adults globally and nearly half of the United States population. Despite the availability of effective therapies, optimal blood pressure control is achieved in fewer than one in four ...
Matthew A. Cavender
wiley   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib, Francisco Emilio Fierro, Maria Ortega Abad, Ricardo Correa   +3 more
wiley   +1 more source

How Common Is Hypercortisolism in Patients With Hypertension? Risk Factors, Epidemiology, and Making a Diagnosis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target‐organ damage.
Omar Al Dhaybi, Deepak L. Bhatt
wiley   +1 more source

Two diagnoses become one? Rare case report of anorexia nervosa and Cushing’s syndrome

Neuropsychiatric Disease and Treatment, 2013
Nadia Sawicka,* Maria Gryczyńska,* Jerzy Sowiński, Monika Tamborska-Zedlewska, Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland*These authors contributed equally to this ...
Sawicka N, Gryczyńska M, Sowiński J, Tamborska-Zedlewska M, Ruchała M   +4 more
doaj  

Cushing syndrome: uncovering Carney complex due to novel PRKAR1A mutation

Endocrinology, Diabetes & Metabolism Case Reports, 2019
Carney complex (CNC) is a rare multiple neoplasia syndrome characterized by spotty pigmentation of the skin and mucosa in association with various non-endocrine and endocrine tumors, including primary pigmented nodular adrenocortical disease (PPNAD).
Catherine D Zhang, Pavel N Pichurin, Aleh Bobr, Melanie L Lyden, William F Young, Irina Bancos   +5 more
doaj   +1 more source

Stapled side‐to‐side anastomosis to treat a pelvic flexure stricture in a miniature horse

Equine Veterinary Education, EarlyView.
Summary Fecaliths are a recognised cause of non‐strangulating colon obstruction in horses. Although they more commonly obstruct the small colon, they can also lodge in the pelvic flexure, requiring enterotomy for removal. Stricture at the enterotomy site is an uncommon but surgically significant complication.
M. Baglioni, N. Berka, P. Matrat, L. Legrand, L. Borde‐Dore, C. de Chaisemartin   +5 more
wiley   +1 more source

Delayed Diagnosis of Ectopic Cushing Syndrome [PDF]

Here, we present the case of a 40-year-old man in whom the diagnosis of ectopic adrenocorticotropin (ACTH) syndrome went unrecognized despite evaluation by multiple providers until it was ultimately suspected by a nephrologist evaluating the patient for ...
Matson, Brooke C, Klein, Klara R, Zeitler, Evan M, Johnson, Steven M, Evron, Joshua M   +4 more
core   +2 more sources

Cushing Syndrome due to Inappropriate Corticosteroid Topical Treatment of Undiagnosed Scabies

Tropical Medicine and Infectious Disease, 2018
The uncontrolled sale of topical corticosteroids has become an important risk factor for the development of iatrogenic Cushing syndrome in children, especially in countries where medications are sold over the counter.
Guadalupe Estrada-Chávez, Roberto Estrada, Daniel Engelman, Jesus Molina, Guadalupe Chávez-López   +4 more
doaj   +1 more source