Results 71 to 80 of about 16,228 (236)

Genetic background and management outcomes in primary bilateral macronodular adrenal hyperplasia: Implications for diagnosis and treatment—A retrospective cohort study

Journal of International Medical Research
Objective Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of Cushing syndrome. Recent evidence, particularly the 2023 European Society of Endocrinology guidelines, clinically classifies cortisol excess into overt Cushing ...
Emine Özlem Gür, Serkan Karaıslı, Ümit Çavdar, Aslı Subaşıoğlu, Özlem Eren, Selda Gücek Hacıyanlı, Barış Önder Pamuk, Mehmet Sercan Ertürk, Mehmet Hacıyanlı   +8 more
doaj   +1 more source

Impact of Osilodrostat on Health‐Related Quality of Life in Cushing's Disease: Analysis of Patient‐Reported Outcomes From the Phase III LINC 3 and LINC 4 Clinical Trials

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Evaluate the effects of osilodrostat short‐ and long‐term treatment on health‐related quality of life (HRQoL) in Cushing's disease. Design LINC 3 and LINC 4 studies (pooled analysis). Patients 185 patients (mean baseline total scores: Cushing's Quality of Life [CushingQoL], 44.0; Beck Depression Inventory II [BDI‐II], 15.6; EuroQol ...
John Newell‐Price, Beverly M. K. Biller, Maria Fleseriu, Beatrice Gueron, Grzegorz Binowski, Anna Paćkowska, Mônica R. Gadelha   +6 more
wiley   +1 more source

Salivary cortisol among subjects with and without Cushing syndrome [PDF]

, 2010
Background: Salivary cortisol measurement is recommended as a screening measure when a Cushing Syndrome is suspected. The proposed cut-off point for a probable diagnosis is 0.16 ug/dL. Aim: To determine salivary cortisol concentrations during the day in
Fiedler Temer, Jenny, Lépez, Macarena, Caamaño, Edgardo, Araya, V., Romero, Carmen   +4 more
core  

Epicardial and Pericardial Adiposity Without Myocardial Steatosis in Cushing Syndrome

, 2021
International audienceAbstract Context Cardiovascular disease is the leading cause of death in patients with Cushing syndrome. Cortisol excess and adverse metabolic profile could increase cardiac fat, which can subsequently impair cardiac structure and ...
Droumaguet, Céline, Young, Jacques, Kachenoura, Nadjia, Prigent, Mikaël, Trabado, Severine, Piedvache, Céline, Marty, Benjamin, Agostini, Helene, Salenave, Sylvie, Wolf, Peter, Kuhn, Emmanuelle, Bouazizi, Khaoula, Blanchard, Anne, Jublanc, Christel, Ajzenberg, Christiane, Redheuil, Alban, Lecoq, Anne-Lise, Chanson, Philippe, Carlier, Pierre, Kamenický, Peter, Fève, Bruno   +20 more
core   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Risk factors for postoperative fever after laparoscopic adrenalectomy focusing on hormones produced: a case control study

BMC Urology
Background Laparoscopic adrenalectomy is widely performed for a number of hormone-producing tumors and postoperative management depends on the hormones produced.
Mizuki Izawa, Toshikazu Takeda, Tadatsugu Anno, Tomohiro Iwasawa, Yota Yasumizu, Nobuyuki Tanaka, Kazuhiro Matsumoto, Shinya Morita, Takeo Kosaka, Ryuichi Mizuno, Hiroshi Asanuma, Mototsugu Oya   +11 more
doaj   +1 more source

Clinical Implications and Research Progress of Salivary Biomarkers for Endocrine and Metabolic Disorders

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Similar to blood, saliva contains a broad range of biomarkers and may offer a non‐invasive, repeatable specimen for endocrine and metabolic assessment. This review aims to synthesise and evaluate recent advances in the clinical translation of salivary biomarkers, while providing a critical assessment of the diagnostic reliability and ...
Chuyan Yu, Jiaying Ni, Qian Dou, Hang Su, Ziyi Zhang, Xiaojing Ma, Qing Dai, Jian Zhou   +7 more
wiley   +1 more source

Cushing’s syndrome in pregnancy

Gynecological Endocrinology, 2014
Cushing's syndrome is a rare condition in the general population and is even less common during pregnancy with only a few cases reported in literature. The diagnosis of Cushing's syndrome may be difficult during pregnancy because the typical features of the disorder and pregnancy may overlap.
Nassi, Rossella, Ladu, Cristina, Vezzosi, Chiara, MANNELLI, MASSIMO   +3 more
openaire   +2 more sources

Factors predicting the duration of adrenal insufficiency in patients successfully treated for Cushing disease and nonmalignant primary adrenal Cushing syndrome

, 2017
Successful treatment of Cushing syndrome causes transient or permanent adrenal insufficiency deriving from endogenous hypercortisolism-induced hypothalamus–pituitary–adrenal–axis suppression.
Pontecorvi, Alfredo, Rota, Carlo Antonio, Paragliola, Rosa Maria, Corsello, Salvatore Maria   +3 more
core   +1 more source

Short‐Term Combined Treatment With Tirzepatide and Metformin for Overweight/Obese Chinese Women With Polycystic Ovary Syndrome: A Prospective, Open‐Label, Randomised Controlled Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims This study aimed to assess the effects of low‐dose tirzepatide combined with metformin (COM) versus metformin (MET) monotherapy in overweight/obese women with polycystic ovary syndrome (PCOS). Materials and Methods Sixty overweight/obese women with PCOS were randomised to the MET group (1000 mg twice daily [BID]) or the COM group (MET ...
Zhuoran Yang, Yuxin Xu, Hu Du, Wenya Liu, Haiyan Chen, Dongfang Liu, Lili Zhang, Cong Wang   +7 more
wiley   +1 more source