Results 51 to 60 of about 16,228 (236)

Outcome of adrenalectomy for subclinical hypercortisolism and Cushing syndrome

, 2017
Background We compared operative and metabolic outcomes in patients with subclinical Cushing syndrome and Cushing syndrome caused by unilateral adrenal lesion, aiming to clarify the role of glucocorticoid replacement treatment in patients with ...
D'Amato, Gerardo, De Crea, Carmela, Bellantone, Rocco Domenico Alfonso, Raffaelli, Marco, Gallucci, Pierpaolo, Lombardi, Celestino Pio   +5 more
core   +1 more source

Inverse association between obesity and intestinal endometriosis: Findings from a cross‐sectional study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates the association between obesity and the presence of bowel endometriosis in patients undergoing surgery. Methods A retrospective cross‐sectional observational study was conducted with patients treated between September 2023 and December 2024, at a specialized endometriosis outpatient clinic of a tertiary hospital ...
Tereza Carolina Fonseca Corrêa, Marco Aurelio Pinho Oliveira   +1 more
wiley   +1 more source

Coagulopathy in Cushing’s Syndrome [PDF]

Neuroendocrinology, 2010
A hypercoagulable state and its consequent increased incidence of thromboembolic complications are reported in patients with Cushing’s syndrome (CS). These alterations are related to cortisol excess that induces prothrombotic changes in blood by several and complex mechanisms including increased levels of clotting factors, mainly factor VIII and von ...
TREMENTINO L, ARNALDI G, APPOLLONI G, DAIDONE, VIVIANA, SCARONI, CARLA, CASONATO, SANDRA, BOSCARO, MARCO   +6 more
openaire   +3 more sources

Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross‐sectional comparative echocardiographic study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari, Melis Pehlivantürk Kizilkan, Musa Öztürk, İlker Ertuğrul, Hayrettin Hakan Aykan, Tevfik Karagöz, Nuray Kanbur, Orhan Derman, Sinem Akgül   +8 more
wiley   +1 more source

Musculoskeletal complications of Cushing syndrome

, 2023
Prolonged exposure to an excess of glucocorticosteroids (GCs), both endogenous and exogenous, leads to a wide range of comorbidities, including cardiovascular, metabolic, psychiatric, and musculoskeletal disorders.
Wojciech Zgliczyński, Alicja Szatko, Dorota Leszczyńska, Lucyna Papierska, Piotr Glinicki   +4 more
core   +1 more source

Unilateral nodular adrenal hyperplasia: Case series

African Journal of Urology, 2016
Introduction: Nodular adrenal hyperplasia is one of rare causes of adrenocortical hyperplasia. The disease usually presents bilaterally. Few publications discussed the possibility of unilateral disease, in association with hyperaldosteronism or Cushing ...
A.F. Kotb, M.A. Atta
doaj   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Metabolic Syndrome in Cushing’s Syndrome [PDF]

Neuroendocrinology, 2010
Although the concept of metabolic syndrome (MetS) as a disease entity continues to be debated, it provides a means by which patients at risk for diabetes and cardiovascular disease can be identified and categorized with routinely available criteria. Insulin resistance plays a central role in these abnormalities.
Philippe, Chanson, Sylvie, Salenave
openaire   +2 more sources

Impact of Fetoscopic Surgery on the Myometrium: Experimental Study in an Ovine Model of Myelomeningocele

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To investigate uterine healing at delivery after fetoscopic myelomeningocele (MMC) closure in an ovine model. Methods This descriptive study was conducted in Romane ewes. Fetal MMC lesions were created after hysterotomy at 75 days of gestation.
Enora Parc, Eugénie Jolivet, Corentin Maillet, Yoann Athiel, Jean‐Marie Jouannic, Lucie Guilbaud   +5 more
wiley   +1 more source