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Adrenal unilateral macronodular hyperplasia is a rare cause of Cushing´s syndrome. We discuss the case of two patients who present Cushing syndrome due to unilateral adrenal hyperplasia.
Yousra Aouinati+4 more
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In the context of ACTH‐dependent Cushing's syndrome, ectopic ACTH secretion from a neuroendocrine tumour is not uncommon, and needs to be carefully differentiated from pituitary‐dependent Cushing's syndrome, Cushing's disease, in order to optimise ...
A. Hayes, A. Grossman
semanticscholar +1 more source
Background McCune–Albright syndrome is a complex disorder encompassing multiple endocrinopathies. These manifestations are secondary to a mutation in the stimulatory G-protein alpha subunit. Cushing syndrome is due to autonomous secretory function of the
Christy Foster+2 more
doaj +1 more source
A patient with Cushing disease lateralizing a pituitary adenoma by inferior petrosal sinus sampling using desmopressin: a case report [PDF]
A 14-year-old girl was referred for evaluation of the etiology of Cushing syndrome. During the previous 2 years, she had experienced weight gain, secondary amenorrhea, growth retardation, and back pain.
Joo Hee Lim+7 more
doaj +1 more source
Kinetics and Inhibition Studies of the L205R Mutant of cAMP-Dependent Protein Kinase Involved in Cushing’s Syndrome [PDF]
Overproduction of cortisol by the hypothalamus–pituitary–adrenal hormone system results in the clinical disorder known as Cushing\u27s syndrome. Genomics studies have identified a key mutation (L205R) in the α‐isoform of the catalytic subunit of cAMP ...
Ellis, Keith C.+3 more
core +2 more sources
Steroids in pediatric eosinophilic esophagitis [PDF]
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core +1 more source
Aortic pulse wave velocity in children with Cushing syndrome: A window into a marker of early cardiovascular disease. [PDF]
ObjectiveTo investigate early signs of cardiovascular arterial remodelling in paediatric patients with Cushing syndrome (CS) in comparison with normative values from healthy children.Study designThe metrics used to assess cardiac health were from ...
Bandettini, Wiphada Patricia+10 more
core +1 more source
Plasma Steroid Metabolome Profiling for Diagnosis and Subtyping Patients with Cushing Syndrome.
BACKGROUND Diagnosis of Cushing syndrome requires a multistep process that includes verification of hypercortisolism followed by identification of the cause of adrenocortical hyperfunction.
G. Eisenhofer+9 more
semanticscholar +1 more source
Corticotropinoma as a Component of Carney Complex. [PDF]
Known germline gene abnormalities cause one-fifth of the pituitary adenomas in children and adolescents, but, in contrast with other pituitary tumor types, the genetic causes of corticotropinomas are largely unknown.
Chittiboina, Prashant+11 more
core +2 more sources
Twist of endocrine scenario: Approach of ectopic Cushing syndrome (review) [PDF]
Ectopic Cushing syndrome or ectopic ACTH (Adrenocorticotropic Hormone) syndrome, a rare but severe condition, is due to a non-pituitary ACTH excess or exceptionally a non-hypothalamic CRH (Corticotropin - Releasing Hormone) hyper-production, usually due ...
Andra MORAR+7 more
doaj +1 more source