Results 31 to 40 of about 3,451 (134)

A Comparison of Regional Decisions for Doses and Administrations of New Drugs: Concordance, Discordance, and Dependencies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Regional differences in approved drug dosages and administration are shaped by complex factors, including clinical data, prior regulatory decisions, and region‐specific considerations. This study investigated how such factors are associated with variations in approved doses across the United States Food and Drug Administration (FDA), European Medicines
Sachiko Mita, Shunsuke Ono
wiley   +1 more source

Ectopic Cushing’s Syndrome as the Initial Presentation of Pulmonary Carcinoid Tumor Managed by Etomidate: A Case Report

open access: yesActa Medica Iranica, 2020
Ectopic increase of adrenocorticotropic hormone (ACTH) or ectopic Cushing syndrome is a rare initial presentation of small cell carcinoma and carcinoid tumor of the lung.
Masoud Mohebbi   +5 more
doaj   +1 more source

Inverse association between obesity and intestinal endometriosis: Findings from a cross‐sectional study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates the association between obesity and the presence of bowel endometriosis in patients undergoing surgery. Methods A retrospective cross‐sectional observational study was conducted with patients treated between September 2023 and December 2024, at a specialized endometriosis outpatient clinic of a tertiary hospital ...
Tereza Carolina Fonseca Corrêa   +1 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

A case report and literature review of Carney complex with atrial adenomyxoma

open access: yesBMC Endocrine Disorders, 2023
Background Carney complex (CNC) is a rare multiple endocrine neoplasia syndrome characterized by mucocutaneous lentigines/ blue nevi, cardiac myxoma and endocrine overactivity.
Jing Xu   +6 more
doaj   +1 more source

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson   +4 more
wiley   +1 more source

Emergence of De Novo Conditions Following Remission of Cushing Syndrome: A Case Report and Scoping Review

open access: yesEndocrinology, Diabetes & Metabolism
Objective Onset and exacerbation of autoimmune, inflammatory or steroid‐responsive conditions have been reported following the remission of Cushing syndrome, leading to challenges in distinguishing a new condition versus expected symptomatology following
Noémie Desgagnés   +4 more
doaj   +1 more source

Adrenocorticotropic Hormone-Independent Cushing Syndrome with Bilateral Cortisol-Secreting Adenomas [PDF]

open access: yesEndocrinology and Metabolism, 2013
A 48-year-old woman was incidentally found to have bilateral adrenal masses, 2.8 cm in diameter on the right, and 2.3 cm and 1.7 cm in diameter on the left, by abdominal computed tomography.
Eu Jeong Ku   +5 more
doaj   +1 more source

The missing woodland story: Implications of 1700 years of stand‐scale change on ‘naturalness’ and managing remnant broadleaved woodlands

open access: yesPeople and Nature, EarlyView.
Abstract Longer‐term perspectives—equivalent to the lifespans of long‐lived trees—are required to fully inform perceptions of ‘naturalness’ used in woodland conservation and management. Stand‐scale dynamics of an old growth temperate woodland are reconstructed using palaeoecological data.
Annabel Everard   +4 more
wiley   +1 more source

A Case of Paraneoplastic Cushing Syndrome Presenting as Hyperglycemic Hyperosmolar Nonketotic Syndrome

open access: yesCase Reports in Oncology, 2017
Carcinoid tumors are neuroendocrine tumors that mainly arise in the gastrointestinal tract, lungs, and bronchi. Bronchopulmonary carcinoids have been associated with Cushing syndrome, which results from ectopic adrenocorticotrophic hormone (ACTH ...
Christina E. Brzezniak   +9 more
doaj   +1 more source

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