Results 41 to 50 of about 35,438 (266)
Central Obesity and BMI Associated with Different Phenotypes of Polycystic Ovary Syndrome in Adolescent [PDF]
Adipose tissue distribution is effective in metabolic complications resulting from obesity. Fat accumulation in the body, particularly increase in visceral fat, is a major risk factor of diabetes and cardiovascular diseases.
Akbaezadeh, M. (Marzieh) +1 more
core +3 more sources
Gel chromatographic characterization of immunoreactive adrenocorticotropin in patients with ACTH hypersecretion [PDF]
We investigated the molecular size of circulating immunoreactive ACTH by gel chromatography in patients with ACTH hypersecretion due to various disorders of the hypothalamic-pituitary-adrenal axis.
A Chatelain +19 more
core +1 more source
Apoplexy of Crooke cell tumour leading to the diagnosis of severe Cushing disease; a case report
Background Patients with Crooke cell tumours present with features of Cushing syndrome or mass effect. There are few reports of patients with Crooke cell tumours presenting due to apoplexy. All of them had silent tumours.
Nipun Lakshitha de Silva +3 more
doaj +1 more source
Monro-Kellie 2.0: The dynamic vascular and venous pathophysiological components of intracranial pressure [PDF]
For 200 years, the ‘closed box’ analogy of intracranial pressure (ICP) has underpinned neurosurgery and neuro-critical care. Cushing conceptualised the Monro-Kellie doctrine stating that a change in blood, brain or CSF volume resulted in reciprocal ...
Wilson, MH
core +1 more source
Management of germ cell tumors in children: Approaches to cure [PDF]
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G. +4 more
core +1 more source
A 45 year old woman was being regularly reviewed in primary and secondary care because of a five year history of type 2 diabetes that had required early insulin treatment; refractory hypertension; and subsequent chronic kidney disease. She had previously described other symptoms, including weight gain, bruising, flushes, and low mood, all of which had ...
Stephanie May +2 more
openaire +5 more sources
Background: Well differentiated bronchial neuroendocrine neoplasms often follow a clinically indolent course and rarely cause ectopic ACTH syndrome. Iatrogenic corticosteroid use is the most common cause of Cushing syndrome and should be considered in ...
Tomas Morales, Shanika Samarasinghe
doaj +1 more source
Familial Micronodular Adrenocortical Disease, Cushing Syndrome, and Mutations of the Gene Encoding Phosphodiesterase 11A4 ( PDE11A) [PDF]
We present the pathologic findings in the adrenal glands of 4 patients, aged 10 to 38 years, with Cushing syndrome and germline inactivating mutations of the gene PDE11A4 that encodes phosphodiesterase11A4. The gene is expressed in the adrenal cortex and
Bertherat, J. +3 more
core +1 more source
Subclinical Cushing's Syndrome [PDF]
Clinically inapparent adrenal masses, or adrenal incidentalomas, are discovered inadvertently in the course of workup or treatment of unrelated disorders. Cortical adenoma is the most frequent type of adrenal incidentaloma accounting for approximately 50% of cases in surgical series and even greater shares in medical series.
TERZOLO, Massimo +3 more
openaire +9 more sources
Endocrine hypertension - Cushing′s syndrome
Hypertension is a major and frequent comorbid finding of Cushing′s syndrome. This review discusses the etiology and pathophysiology of hypertension in Cushing′s syndrome, while suggesting methods of management of this condition.
Yashpal Singh +2 more
doaj +1 more source

