Results 51 to 60 of about 7,499 (259)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

CUSP FORMS WITH RATIONAL EVEN PERIODS

open access: yesKyushu Journal of Mathematics, 2023
Let \(\mathbb{D}\) denote the set of all discriminants \[ \mathbb{D}=\{D\in \mathbb{Z}:D\equiv 0,1(\text{mod}4)\} \] and let \(Q_{D}\) denote the set of all integral binary quadratic forms \[ Q_{D}(x,y)=ax^{2}+bxy+cy^{2} \] shortly, \(Q_{D}=[a,b,c]\), of discriminant \(D=b^{2}-4ac\).
openaire   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Relating Siegel cusp forms to Siegel–Maaß forms

open access: yesResearch in Number Theory, 2022
AbstractIn this paper we generalize a well-known isomorphism between the space of cusp forms of weight k for a Fuchsian subgroup of the first kind $$\Gamma \subset \mathrm {SL}_{2}({\mathbb {R}})$$ Γ ⊂ SL 2
Jürg Kramer, Antareep Mandal
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

On the coefficients of cusp forms [PDF]

open access: yesMathematical Research Letters, 1997
Fix a cuspidal representation \(\pi\) of \(GL(2)\) over (the adele ring of) a number field \(F\), and write \(a_v\) for the sum of the Hecke eigenvalues of \(\pi\) at a place \(v\) of \(F\) where \(\pi\) is unramified. Ramanujan's conjecture for \(\pi\) is equivalent to \(|a_v|\leq 2\) for all \(v\).
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The protoconid: a key cusp in lower molars. Evidence from a recent modern human population

open access: yesAnnals of Human Biology, 2022
Background The molar (M) size sequence in the genus Homo is decreasing and the general pattern in Homo sapiens is M1> M2 > M3. Aim To gain a better understanding of the reduction patterns of M components (cusps), we aim to assess the area of the ...
José María Bermúdez de Castro   +3 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Poincaré series for modular graph forms at depth two. Part I. Seeds and Laplace systems

open access: yesJournal of High Energy Physics, 2022
We derive new Poincaré-series representations for infinite families of non-holomorphic modular invariant functions that include modular graph forms as they appear in the low-energy expansion of closed-string scattering amplitudes at genus one.
Daniele Dorigoni   +2 more
doaj   +1 more source

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