Results 71 to 80 of about 2,587,264 (278)
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
The protoconid: a key cusp in lower molars. Evidence from a recent modern human population
Annals of Human Biology, 2022 Background The molar (M) size sequence in the genus Homo is decreasing and the general pattern in Homo sapiens is M1> M2 > M3. Aim To gain a better understanding of the reduction patterns of M components (cusps), we aim to assess the area of the ...
José María Bermúdez de Castro +3 more
doaj +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Poincaré series for modular graph forms at depth two. Part I. Seeds and Laplace systems
Journal of High Energy Physics, 2022 We derive new Poincaré-series representations for infinite families of non-holomorphic modular invariant functions that include modular graph forms as they appear in the low-energy expansion of closed-string scattering amplitudes at genus one.
Daniele Dorigoni +2 more
doaj +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
On the arithmetic nature of coefficients of multiplicative eta-functions
Вестник Самарского университета: Естественнонаучная серияIn the article we study the arithmetic nature of the coefficients of multiplicative eta-products, also called McKay functions. For some functions it is possible to establish Hecke correspondence between the coefficients of McKay and Hecke grossen ...
G. V. Voskresenskaya
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Nonlinear Analysis, 2020 In the paper, joint discrete universality theorems on the simultaneous approximation of a collection of analytic functions by a collection of discrete shifts of zeta-functions attached to normalized Hecke-eigen cusp forms are obtained.
Antanas Laurinčikas +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Cluster boundary layer measurements and optical observations at magnetically conjugate sites [PDF]
Annales Geophysicae, 2001 The Cluster spacecraft experienced several boundary layer encounters when flying outbound from the magnetosphere to the magnetosheath in the dusk sector on 14 January 2001.
J. Moen +10 more
doaj +1 more source