Results 81 to 90 of about 1,546 (196)

Our clinical experience on renal protection with custadiol solution during juxtarenal clamping in open repair of abdominal aorta aneurysm

Turkish Journal of Vascular Surgery, 2023
Aim: Technological developments on endovascular stents have increased the percutaneous repair of abdominal aortic aneurysm(AAAs). Open repair of abdominal aneurysm remains as the first option for treatment of aneurysm with compromising necks that need ...
Mugisha Kyaruzi, Unal Aydin, Muhammed Bayram, Ersin Kadirogullari, Mustafa Can Kaplan   +4 more
doaj  

Hypothermic machine perfusion in uterus transplantation in a porcine model: A proof of concept and the first results in graft preservation

Acta Obstetricia et Gynecologica Scandinavica, Volume 104, Issue 3, Page 461-473, March 2025.
The first animal model of hypothermic machine perfusion in uterus transplantation showed that this new technique was not only feasible, but it also seemed to provide a better preparation for ischaemia‐reperfusion phenomena despite a significantly longer warm ischaemia time.
Carla Héléna Sousa, Marion Mercier, Nathalie Rioux‐Leclercq, Erwan Flecher, Claude Bendavid, David Val‐Laillet, Juliette Ferrant, Sylvie Jaillard, Emma Loiseau, Julien Branchereau, Yanis Berkane, Krystel Nyangoh Timoh, Isis Carton, Maëla Le Lous, Vincent Lavoue, Ludivine Dion   +15 more
wiley   +1 more source

Establishing a physiologically based pharmacokinetic framework for aldehyde oxidase and dual aldehyde oxidase‐CYP substrates

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 1, Page 164-178, January 2025.
Abstract Aldehyde oxidase (AO) contributes to the clearance of many approved and investigational small molecule drugs, which are often dual substrates of AO and drug‐metabolizing enzymes such as cytochrome P450s (CYPs). As such, the lack of established framework for quantitative translation of the clinical pharmacologic correlates of AO‐mediated ...
Nihan Izat, Jayaprakasam Bolleddula, Pasquale Carione, Leticia Huertas Valentin, Robert S. Jones, Priyanka Kulkarni, Darren Moss, Vincent C. Peterkin, Dan‐Dan Tian, Andrea Treyer, Karthik Venkatakrishnan, Michael A. Zientek, Jill Barber, J. Brian Houston, Aleksandra Galetin, Daniel Scotcher   +15 more
wiley   +1 more source

Open surgical repair of an abdominal aortic aneurysm in a renal transplant recipient

Turkish Journal of Vascular Surgery, 2021
Abdominal aortic aneurysm (AAA) surgical repair in renal transplant recipients requires alternative techniques for the protection of the transplanted kidney against ischemia and reperfusion injury.
Unal Aydın, Muhammed Bayram, Safa Gode, Mugisha Kyaruzi, Onur Şen   +4 more
doaj  

Influence of pericardium on ventricular mechanical interdependence in an isolated biventricular working pig heart model

The Journal of Physiology, Volume 603, Issue 2, Page 285-300, 15 January 2025.
Abstract figure legend Schematic representation of the experimental workflow and main results of left and right ventricular outflows obtained before and after ablation of the pericardium, on isolated pig hearts perfused in biventricular working mode. Left and right ventricular haemodynamics were assessed in response to changes in left and right atrial ...
Fanny Vaillant, Emma Abell, Laura R. Bear, Guido Caluori, Charly Belterman, Ruben Coronel, Sylvain Ploux, Pierre Dos Santos   +7 more
wiley   +1 more source

Myocardial protection during minimally invasive cardiac surgery through right mini-thoracotomy

, 2017
Background: Myocardial damage is an independent predictor of adverse outcome following cardiac surgery and myocardial protection is one of the key factors to achieve successful outcomes. Cardioplegia with Custodiol is currently the most used cardioplegia
Guida P., Rociola R., Quagliara T. A. P., Mastro F., De Palo M., Nanna D., Lionetti G., Paparella D.   +7 more
core   +2 more sources

Ex vivo kidney resection in pharmacological cold ischemia followed by orthotopic autotransplantation

Трансплантология (Москва), 2016
Introduction. One of the priorities in oncology includes the development of alternative organoprotection treatments for renal cell carcinoma (RCC) of intraparenchymal and central tumor location.Study objective was to develop the method of extracorporeal ...
A. A. Gritskevich, S. S. P'yanikin, Z. A. Adyrkhaev, Yu. A. Stepanova, V. V. Kazennov, A. E. Zotikov, A. A. Teplov, A. Sh. Revishvili   +7 more
doaj  

Effects of ischemic preconditioning associated to different preservation solutions in protecting the intestinal graft Efeitos do precondicionamento isquêmico associado a diferentes soluções de preservação na proteção do enxerto intestinal

Acta Cirúrgica Brasileira, 2011
PURPOSE: To evaluate the effects of ischemic preconditioning (IPC) associate with different preservation solutions, in the protecting of gut. METHODS: Four groups of 14 rats underwent laparotomy and collecting 20 cm of ileum, for preservation, at 4ºC, in
José de Souza Neves, Marcos de Souza Abrahão, Alcides Augusto Salzedas Netto, Edna Frasson de Souza Montero, Adriano Miziara Gonzalez   +4 more
doaj   +1 more source

CUSTODIOL SOLUTION AND COLD BLOOD CARDIOPLEGIA IN SWITCH OPERATION: RETROSPECTIVE ANALYSIS IN A SINGLE CENTER

, 2016
Background The cardioplegia is one of the most significant tools used to increase myocardial protection. The aim of our study is to compare the use of Custodiol solution versus intermitted blood cardioplegia in a retrospective analysis of data for ...
Poli V, Arcieri L, Giordano R, Cantinotti M, Moschetti R, Pak V, Murzi B, Maizza A, N, Melo M, Assanta   +10 more
core  

Comparison between Bretschneider -HTK solution and antegrade cold blood cardioplegia as a method for myocardial protection in thoracic aortic surgery

, 2022
Background: Cardiac surgeons demand a cardioplegic solution providing extended durations of myocardial protection due to the increasing complexity of cardiac surgical procedures, especially thoracic aortic operations which require extended myocardial ...
Soliman, Said Abdelaziz, Ragab, Ihab, Salah, M. (Maged), Elsharkawy, A. (Ahmed), Dawoud, O. (Omar), Elsharkawy, Ahmed, Salah, Maged, Dawoud, Omar, Ragab, I. (Ihab), Soliman, S. A. (Said)   +9 more
core   +1 more source