Results 71 to 80 of about 1,586 (155)

Protective effects of neutrophil serine protease inhibition against ischemia–reperfusion injury in lung or heart transplantation

The FEBS Journal, Volume 292, Issue 22, Page 5877-5887, November 2025.
A major complication of organ transplantation is primary graft dysfunction, which represents the leading cause of early post‐transplantation morbidity and mortality. Pre‐operative depletion of neutrophil serine proteases in circulating neutrophils by pretreatment with a cathepsin C inhibitor in recipients could prevent early post‐operative ...
Sevil Korkmaz‐Icöz, Gábor Szabó, Artur Gieldon, Patrick P. McDonald, Alexey Dashkevich, Ali Önder Yildirim, Brice Korkmaz   +6 more
wiley   +1 more source

Evaluation of the prospects for developing a next-generation perfusion solution for hypothermic oxygenated preservation of donor organs

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Background. Ischemia-reperfusion injury remains a central challenge in clinical transplantology, determining outcomes particularly when using organs from expanded criteria donors and donors after circulatory death.
M. S. Novruzbekov, B. I. Yaremin, A. G. Balkarov, B. I. Kazymov, P. O. Svischeva, O. N. Pavlova, S. M. Khanova   +6 more
doaj   +1 more source

Our clinical experience on renal protection with custadiol solution during juxtarenal clamping in open repair of abdominal aorta aneurysm

Turkish Journal of Vascular Surgery, 2023
Aim: Technological developments on endovascular stents have increased the percutaneous repair of abdominal aortic aneurysm(AAAs). Open repair of abdominal aneurysm remains as the first option for treatment of aneurysm with compromising necks that need ...
Mugisha Kyaruzi, Unal Aydin, Muhammed Bayram, Ersin Kadirogullari, Mustafa Can Kaplan   +4 more
doaj  

Portal Venous Drainage Modulates Inflammatory and Apoptotic Responses in a Swine Model of Living Donor Intestinal Transplantation

Pediatric Transplantation, Volume 29, Issue 7, November 2025.
Portal venous drainage in a swine model of living‐donor intestinal transplantation promoted a more balanced immunometabolic profile, with early apoptotic modulation and increased IL‐1α expression, suggesting improved mucosal adaptation compared with systemic drainage.
Guilherme F. Paganoti, Uenis Tannuri, Alessandro R. Belon, Josiane O. Gonçalves, Suellen Serafini, Raimundo R. N. Guimarães, Felipe Y. Matsushita, Ana Cristina A. Tannuri   +7 more
wiley   +1 more source

Lipocalin‐2 Restores Soluble Guanylyl Cyclase‐Dependent Dilation of the Afferent Arteriole After Renal Transplantation or Ex Vivo Hypoxia/Reoxygenation in Mice

Acta Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Dilatory microvascular function is impaired in ischemia/reperfusion injury in the kidney. Nitric oxide independent activators of soluble guanylyl cyclase (sGC) provide renal protection by dilating microvessels and preserving perfusion, but their efficacy declines after severe hypoxia.
Liang Zhao, Minze Xu, Anna Maria Pfefferkorn, Cem Erdogan, Hubert Schwelberger, Pinchao Wang, Pratik Hemant Khedkar, Marc Eigen, Falk‐Bach Lichtenberger, Rusan Catar, En Yin Lai, Felix Aigner, Pontus B. Persson, Igor Maximilian Sauer, Andreas Patzak, Muhammad Imtiaz Ashraf   +15 more
wiley   +1 more source

Ex vivo kidney resection in pharmacological cold ischemia followed by orthotopic autotransplantation

Трансплантология (Москва), 2016
Introduction. One of the priorities in oncology includes the development of alternative organoprotection treatments for renal cell carcinoma (RCC) of intraparenchymal and central tumor location.Study objective was to develop the method of extracorporeal ...
A. A. Gritskevich, S. S. P'yanikin, Z. A. Adyrkhaev, Yu. A. Stepanova, V. V. Kazennov, A. E. Zotikov, A. A. Teplov, A. Sh. Revishvili   +7 more
doaj  

Open surgical repair of an abdominal aortic aneurysm in a renal transplant recipient

Turkish Journal of Vascular Surgery, 2021
Abdominal aortic aneurysm (AAA) surgical repair in renal transplant recipients requires alternative techniques for the protection of the transplanted kidney against ischemia and reperfusion injury.
Unal Aydın, Muhammed Bayram, Safa Gode, Mugisha Kyaruzi, Onur Şen   +4 more
doaj  

CUSTODIOL SOLUTION AND COLD BLOOD CARDIOPLEGIA IN SWITCH OPERATION: RETROSPECTIVE ANALYSIS IN A SINGLE CENTER

, 2016
Background The cardioplegia is one of the most significant tools used to increase myocardial protection. The aim of our study is to compare the use of Custodiol solution versus intermitted blood cardioplegia in a retrospective analysis of data for ...
Poli V, Arcieri L, Giordano R, Cantinotti M, Moschetti R, Pak V, Murzi B, Maizza A, N, Melo M, Assanta   +10 more
core  

Effects of ischemic preconditioning associated to different preservation solutions in protecting the intestinal graft Efeitos do precondicionamento isquêmico associado a diferentes soluções de preservação na proteção do enxerto intestinal

Acta Cirúrgica Brasileira, 2011
PURPOSE: To evaluate the effects of ischemic preconditioning (IPC) associate with different preservation solutions, in the protecting of gut. METHODS: Four groups of 14 rats underwent laparotomy and collecting 20 cm of ileum, for preservation, at 4ºC, in
José de Souza Neves, Marcos de Souza Abrahão, Alcides Augusto Salzedas Netto, Edna Frasson de Souza Montero, Adriano Miziara Gonzalez   +4 more
doaj   +1 more source

Comparison Between Custodiol and Blood-enriched Cardioplegia on Myocardial Protection During Double Valve Replacement Surgeries [PDF]

Al-Azhar International Medical Journal
Background: Cardioplegia is necessary during heart surgery to lessen the myocardium's metabolic needs and avoid osmotic, electrolytic, and pH imbalances.
El-Husseiny E. Gamil, Hosny M. El Sallab, Mohamed H. Mahmoud, Asmaa G Shahien   +3 more
doaj   +1 more source