Results 61 to 70 of about 2,008,361 (358)

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

Advanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo, Megi Maci, April M. Stafford, Morgan R. Miller, Stephen J. Perle, Shuzo Inagaki, Shusaku Takahashi, Heather Brown‐Harding, Linda Liang, Alex Lovely, Moustafa Algamal, Rebecca L. Gillani, Theodore J. Zwang, Douglas Richardson, Janice R. Naegele, Daniel Vogt, Ksenia V. Kastanenka   +16 more
wiley   +1 more source

Short Term Steel Plant Load Forecasting Based on Multi Sequence LSTM Recurrent Neural Network and Self‐Organizing Neural Network

The Journal of Engineering
Due to the complex patterns, numerous influencing factors, strong temporal characteristics, and mostly nonlinear relationships of power load in steel enterprises, it has become a hot research topic in recent years.
Zhiwei Wang, Maomao Ding, Zhongwei Cai, Wei Yu, Xin Luo   +4 more
doaj   +1 more source

Feasibility exploration analysis of AR virtual verification method of civil aircraft maintenance program

Hangkong gongcheng jinzhan
The difficulty of verifying civil aircraft manuals lies in the guarantee of verification resources，and there is an urgent need to develop new verification methods to achieve efficient and low-cost manual verification.
SUN Hongli, WANG Hongchao, ZHANG Yajie, QIAO Wanxin, ZHAO Xincan   +4 more
doaj   +1 more source

An investigation toward purchase intention of halal beef from traditional market: A TPB perspective

Asian Journal of Islamic Management, 2020
Purpose: The aim of this study was to investigate the consumer behavior toward purchasing intention of halal beef in Yogyakarta traditional Market, by using the Theory of Planned Behavior (TPB) that consisted of attitude behavior, subjective norm and ...
Mohammad Khibran
doaj   +1 more source

Predicting Multi-class Customer Profiles Based on Transactions: a Case Study in Food Sales [PDF]

, 2012
Predicting the class of a customer profile is a key task in marketing, which enables businesses to approach the right customer with the right product at the right time through the right channel to satisfy the customer's evolving needs.
Apeh, E., Gabrys, Bogdan, Pechenizkiy, Mykola, Zliobaite, Indre   +3 more
core   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, EarlyView.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

IMC customer-based perception: strategic antecedents and consequences on post-purchase customer behaviour [PDF]

, 2017
Last decades Integrated Marketing Communications (IMC) have been mainly analysed from a managerial perspective, overlooking the customer opinion. Thus, this research studies IMC customer-based perception, its strategic antecedents and consequences on ...
Alarcón del Amo, María del Carmen, Butkouskaya, Vera, Llonch Andreu, Joan, Rondán Cataluña, Francisco Javier (Coordinador)   +3 more
core  

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

An Exploration of Customer-Defined Perception of Market Orientation:Antecedents and Consequences [PDF]

, 2011
As universities worldwide are being required to be more responsive to the needs of their customers, the literature has focused on identifying exactly who is the customer in the higher education industry.
Akinyele, S.T.
core