Results 71 to 80 of about 507,507 (315)

Measuring Risk-adjusted Customer Lifetime Value and its Impact on Relationship Marketing Strategies and Shareholder Value [PDF]

, 2005
The calculations which underlie efforts to balance marketing spending on customer acquisition and customer retention are usually based on either single- period customer profitability or forecasts of customer lifetime value (CLTV).
Ryals, Lynette, Knox, Simon
core   +1 more source

Ferritinophagy Rewires Carnitine‐Dependent Lipid Metabolism to Inhibit PRRSV and IAV Replication

Advanced Science, EarlyView.
NCOA4‐mediated ferritinophagy reprograms carnitine metabolism by disrupting Fe‐S cluster biogenesis, thereby establishing an iron‐lipid axis that suppresses various viruses, including PRRSV and IAV. However, viruses counteract this mechanism by degrading NCOA4.
Kaifeng Guan, Chenyang Yuan, Zekun Meng, Yanan Wang, Xueying Zhai, Chunjie Huang, Xiang Zhou, Gaiping Zhang   +7 more
wiley   +1 more source

Construction and key technologies discussion of digital smart laboratory for power measurement

Diance yu yibiao
With the vigorous development of the digital economy and the rapid construction of novel power system, deeply integrating advanced digital technology with power measurement technology and building a digital power measurement smart laboratory is an ...
TONG Xia, CHENG Pengshen, LI Xuecheng, XIE Jinjun, JIN Yang, LI Ji   +5 more
doaj   +1 more source

Optimising customer support in contact centres using soft computing approach [PDF]

, 2006
This paper describes the research and development of a methodology for optimising the customer support in contact centres (CC) using a soft computing approach.
Tiwari, Ashutosh, Roy, Rajkumar, Shah, Satya Ramesh   +2 more
core  

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

Advanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang, Xinxin Zou, Jiansong Zhou, Qinmiao Sun, Dahua Chen   +4 more
wiley   +1 more source

Improving Customer Satisfaction: Changes as a Result of Customer Value Discovery [PDF]

, 2008
Objective: To identify Gold Standard Services for customers in an academic library and determine whether interventions following the identification of customer value increased student satisfaction.Methods: “Customer Discovery Workshops” were undertaken ...
McKnight, S, Mike Berrington, Berrington, M, Susan McKnight   +3 more
core  

Intramolecular Interactions between Folded and Disordered Regions Shape Ubiquilin Structure and Function

Advanced Science, EarlyView.
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo, Nirbhik Acharya, Maxwell B. Watkins, Carlos A. Castañeda, Shahar Sukenik   +4 more
wiley   +1 more source

Feasibility exploration analysis of AR virtual verification method of civil aircraft maintenance program

Hangkong gongcheng jinzhan
The difficulty of verifying civil aircraft manuals lies in the guarantee of verification resources，and there is an urgent need to develop new verification methods to achieve efficient and low-cost manual verification.
SUN Hongli, WANG Hongchao, ZHANG Yajie, QIAO Wanxin, ZHAO Xincan   +4 more
doaj   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

Advanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando, Emanuele Buratti, Francesca Paron   +2 more
wiley   +1 more source

A federated collaborative short-term industrial load forecasting method integrating meta-learning and differentiated privacy allocation

Frontiers in Energy Research
Short-term load forecasting for industrial users is often limited by scarce local data and heterogeneous load patterns, while cross-factory collaboration raises serious privacy concerns due to production-sensitive information.
Maomao Ding, Zhongwei Cai, Boyang Chen, Junjie Han   +3 more
doaj   +1 more source