Results 71 to 80 of about 2,008,361 (358)

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source

Establishment method of civil aircraft abnormal operation procedure items

Hangkong gongcheng jinzhan
Abnormal procedures are the important basis for the flight crew to handle emergency conditions. There is no current establishment method of procedures items，which makes redundancy or omission may easily occur in the procedure items.
ZHANG Congyuan, YANG Yanyan
doaj   +1 more source

'Insights' continuous publication case study

Insights: The UKSG Journal, 2019
'Insights: the UKSG Journal' switched to a continuous publication model in early 2018, following a decision by the Editorial Board in November 2017. The prospect of a switch had been discussed a number of times previously.
Charlie Rapple
doaj   +1 more source

HR Practices and Customer Satisfaction: The Mediating Link of Commitment [PDF]

, 2001
This research examined organizational commitment as a mediator between HR practices and customer satisfaction of 35 job groups from 13 service firm business units.
Gardner , Timothy M., Moynihan, Lisa M., Park, Hyeon Jeong, Wright, Patrick M.   +3 more
core   +1 more source

CUSTOMER INTIMACY, CUSTOMERS EXPERIENCE, CUSTOMER SATISFACTION, CUSTOMER BONDING DAN CUSTOMER VALUE DALAM LOYALITAS NASABAH DI BANK SYARIAH

Ekonomi & Bisnis, 2023
Pada perkembangan perekonomian di Indonesia yang semakin maju, khususnya pada sektor perbankan syariah. Dengan pertumbuhan perbankan syariah di Indonesia telah menciptakan banyak investor dan nasabah dengan berbagai penghimpunan dana. Tingginya minat masyarakat terhadap perbankan syariah untuk menabung dan melakukan pembiayaan membuat sektor perbankan ...
Khansa Lathifah Vitram, Muhammad Iqbal Rasa, Suharto Harto   +2 more
openaire   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

Identifying successful sales and marketing strategies that affect customer loyalty in a coffee shop [PDF]

, 2017
.Most small businesses such as coffee shops are concerned with customer loyalty and satisfaction, and increasing profitability. Marketing strategy becomes important when customer loyalty is low.
Huang, Yijia, Wood, Brent
core   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Research on automatic generation of civil aircraft consumable product manual based on S1000D specification

Hangkong gongcheng jinzhan
At present，consumable product manual（CPM）is written manually，which wastes manpower and is easy to produce inconsistent manual contents. To solve this problem，a method of automatic generation of homologous manual based on S1000D standard is studied.
LI Mengxia, YANG Yang
doaj   +1 more source

Time‐Efficient and Informatic‐Skill‐Light Gap‐Filling for Telomere‐to‐Telomere Genome Assembly

Advanced Science, EarlyView.
The paper introduces a novel auxiliary software toolbox GapSuite, consisting of two tools Gap‐Aid and Gap‐Graph, which guides users to fill gaps in chromosome‐level genome assembly using sequence‐extension‐based and assembly‐graph‐based strategies. The two tools enable users with limited informatics expertise to efficiently complete gap‐filling on ...
Dong Xu, Xianjia Zhao, Lianguang Shang, Shaolong Tian, Yanchun Li, Huaming Wen, Qiang Xu, Dongxi Li, Weihua Pan   +8 more
wiley   +1 more source