Results 61 to 70 of about 880,418 (366)

Developing and Adapting the Existing Automotive Business Model: A Case Study

open access: yesEconomics and Culture, 2022
Research purpose. The paper examines how to successfully adapt the existing business model, develop and introduce a new program in a company and gain new customers.
Faganel Armand, Jeran Tomaž
doaj   +1 more source

Intramolecular Interactions between Folded and Disordered Regions Shape Ubiquilin Structure and Function

open access: yesAdvanced Science, EarlyView.
Ubiquilin (UBQLN), like many other human proteins, contains both well‐folded and disordered regions. Here, we show that intramolecular interactions between disordered regions and folded domains modulate between open and closed topologies of UBQLN proteins, altering their structure and function.
Jessica K. Niblo   +4 more
wiley   +1 more source

The Susceptibility of Meningococci to the Antimicrobial Agents in Moscow 2006 - 2015

open access: yesЭпидемиология и вакцинопрофилактика, 2016
Relevance. One of the prognostic criteria meningococcal infection (MI) epidemic status process is the increasing number of resistant to antibiotics meningococcal strains.
M. A. Koroleva   +3 more
doaj   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

open access: yesAdvanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando   +2 more
wiley   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

open access: yesAdvanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li   +13 more
wiley   +1 more source

Sustainable business models: integrating employees, customers and technology [PDF]

open access: yes, 2020
This Special Issue of the Journal of Business & Industrial Marketing has the same title as the 23rd International Conference CBIM 2018 (June 18-20, 2018, Madrid, Spain) “Sustainable Business Models: Integrating Employees, Customers and Technology”.
Ruiz-Alba, J., Martín-Peña, M.
core   +1 more source

Safety of Sodium‐Ion Batteries: Evaluation and Perspective from Component Materials to Cells, Modules, and Packs

open access: yesAdvanced Energy Materials, EarlyView.
This review provides a bottom‐up evaluation of sodium‐ion battery safety, linking material degradation mechanisms, cell engineering parameters, and module/pack assembly. It emphasizes that understanding intrinsic material stability and establishing coordinated engineering control across hierarchical levels are vital for preventing degradation coupling ...
Won‐Gwang Lim   +5 more
wiley   +1 more source

Epidemiological Aspects of Pneumococcal Meningitis in the Russian Federation

open access: yesЭпидемиология и вакцинопрофилактика, 2016
Introduction. Pneumococcal meningitis (PM) refers to severe manifestations of pneumococcal disease with high mortality and frequent post-infectious complications.
I. S. Koroleva   +3 more
doaj   +1 more source

Features of Knowledge Management Implementation in the Context of the Covid-19 Pandemic [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2022
This study focuses on proactive managerial actions, reflecting the implementation of knowledge management in the context of the Covid-19 pandemic. Management was compelled by the Covid-19 pandemic, and the transformation of preliminary information into ...
Adina Eleonora Spînu   +2 more
doaj  

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