Results 41 to 50 of about 43,528 (267)

Customer satisfaction, customer delight, customer retention and customer loyalty: Borderlines and insights

open access: yesUncertain Supply Chain Management, 2022
The aim of this study is to investigate the effects of customer satisfaction and customer delight on customer loyalty through customer retention. Data were collected using a questionnaire developed based on the literature and administered to a sample of restaurant customers consisting of 376 customers. Using IBM SPSS and AMOS software for data analyses,
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Implementing Big Data Analytics in E-Commerce: Vendor and Customer View

open access: yesIEEE Access, 2021
Due to the information revolution, one of the biggest challenges of e-commerce is the huge data that needs to be processed and analyzed to gain benefits from it.
Sarah S. Alrumiah, Mohammed Hadwan
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

ESTIMATION OF ECONOMIC EFFECTS FROM PRODUCT CUSTOMIZATION OF RUSSIAN INDUSTRIAL ENTERPRISES

open access: yesСтратегические решения и риск-менеджмент, 2022
The development of digital production technologies, taking place within the framework of the global fourth industrial revolution, creates conditions for increasing the level of customization of industrial production, i.e.
S. A. Titov, N. V. Titova
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Optimal Software Versioning Strategy Considering Customization and Consumer Deliberation Behavior

open access: yesJournal of Theoretical and Applied Electronic Commerce Research, 2023
This study investigates the optimal versioning problem when a monopoly software provider bears the deliberation cost to help reduce consumer uncertainty about SaaS customization.
Wenjun Shu   +3 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Assessing Operability on Berthed Ships. Common Approaches, Present and Future Lines

open access: yesJournal of Marine Science and Engineering, 2020
The revenue of a ship company, a terminal, a port and even the whole logistic chain largely depends on the performance of (un)loading operations inside port areas. However, they are conditioned by met-ocean agents that exert stresses on fixed structures,
Rafael Molina-Sanchez   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy