Results 161 to 170 of about 14,368 (299)

Challenges in radiopharmaceutical importation across six Southern African Development Community countries: an exploratory study. [PDF]

Front Med (Lausanne)
Mkhombo VG, Mosima L, Summers B.
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Access to praziquantel in Italy: persistent gaps and ongoing responses amid a Europe-wide shortage. [PDF]

Infect Dis Poverty
Marrone R, Camponi C, Cammarata S, Di Giorgio D, Nisticò RG, Napoli C.   +5 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Alfa-PVP: Why Does Finland Stick Out? [PDF]

Nordisk Alkohol Nark
Hellman M.
europepmc   +1 more source

REQUIREMENTS FOR THE FUNCTIONING OF CUSTOMS AUTHORITIES

Juridical scientific and electronic journal, 2020
openaire   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

An Imported Case of Dengue/Zika Coinfection - Sichuan Province, China, 2026. [PDF]

China CDC Wkly
Hu L, Tian L, Yan K, Zhang S, Xie W, Feng J, Du X, Wang L, Liu W, Luo J, Tang F, Yang N, Wang Y, Peng Y, Chen Z, Zhang Q, Meng J, Lu R.   +17 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Strengthening microbial genomics capacity in Africa for epidemic preparedness: key lessons from the AFROSCREEN programme. [PDF]

J Glob Health
AFROSCREEN consortium.
europepmc   +1 more source