Results 181 to 190 of about 1,779,882 (345)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Successful Cross-Agency Model for Collaborative Response to Imported Infectious Disease: Investigation and Management of the First Confirmed Clade Ia Mpox Case in Shanghai, China. [PDF]

Trop Med Infect Dis
Cao Z, Xu F, Huang X, Shen Y, Xin X, Ai L, Pan H, Wu H.   +7 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Import of antibiotics by air travellers - an observational study at airports in Sweden and Norway. [PDF]

Antimicrob Resist Infect Control
Lenander C, Persson A, Al Hassani H, Hedin K, Høye S, Jensen S, Sundvall PD, Sundvall S, Moberg A.   +8 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

ASSESSMENT OF HR RISKS IN CUSTOMS AUTHORITIES

The transformation of customs administration processes, involving automation and digitalization, is increasing the demands on the professional and digital competence of customs officials.
K. Trubicyn, O. Kalmykova, Elena Muller
core   +1 more source

Bridging policy and practice: implementation of emerging infectious disease risk assessment in China from a One Health perspective. [PDF]

Sci One Health
Li T, Qiang N, Jia L, Zhu Z, Feng X, Zhang X, Ran J, Han L.   +7 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Laughing Song, The

B flat majorAllegroMy story yes c'est amoureuse (C'est l'histoire amoureuse)238(From cover) Operatic ...
http://id.loc.gov/authorities/names/n80079937, Auber, D. F. E. (Daniel François Esprit), 1782-1871   +1 more
core  

Conflict-Related Disruption of Oncology Drug Supply in the Gulf and Measures to Maintain Cancer Care Continuity. [PDF]

Glob J Qual Saf Healthc
Abusanad A, Esba LCA, Kullab S.
europepmc   +1 more source