Results 171 to 180 of about 1,779,882 (345)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Barcarolle

open access: yes, 1910
D majorModerato8632-3(From cover) The Standard Operas: Transcriptions and ...
Offenbach, Jacques, 1819-1880   +1 more
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

I Am Titania

open access: yes
B flat majorAh! pour ce soir (Ah! per stassera / Ah!
Thomas, Ambroise, 1811-1896   +1 more
core  

IMPROVING CUSTOMS CONTROL PROCEDURES

open access: yesМодели, системы, сети в экономике, технике, природе и обществе
Background. The foreign economic activity of the region is a significant factor in its successful development. The purpose of the study is to identify possible errors and violations committed by participants in foreign economic activity and customs ...
V.Yu. Sinyavin, M.A. Dolmatov
doaj   +1 more source

Regulation of interaction between customs authorities and state authorities in Ukraine

open access: yesPublic administration and customs administration
O. Krytenko, V. H. Kovalov
semanticscholar   +1 more source

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