Results 131 to 140 of about 5,623 (243)

Spatial and social determinants of the 1857 yellow fever epidemic in Lisbon. [PDF]

PLoS Negl Trop Dis
Bates IH, Li SL, Parag KV, Gaythorpe KAM, Abecasis AB, Smallman-Raynor M, Faria NR.   +6 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cultural and Social Determinants of Physical Therapy Rehabilitation in Saudi Arabia: A Narrative Review. [PDF]

Healthcare (Basel)
Alonazi A.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Crossing Borders of Care: The Professionalization of Women in Nursing and China-US Collaboration at Xiangya, 1909-1926. [PDF]

Nurs Inq
Tang Y, Tobbell D.
europepmc   +1 more source

Customs and Customs Duties in China - Evolution, Reforms and Challenges

, 2016
Depuis l'application de la politique d'ouverture et de réforme en Chine dans les années 1980, la douane et les droits de douanes de la Chine ont connu une évolution considérable suite à des réformes successives et importantes. Ces réformes ont été menées dans un premier temps afin de répondre aux besoins de l'application de la politique de réforme et d'
openaire   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Expedient truth-telling in the ICU: a qualitative content analysis. [PDF]

BMC Nurs
Cheraghi R, Hassankhani H, Ebrahimi H, Behshid M, Shahbazi S, Seif-Farshad M.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Impact of China's Accession Protocol on its participation in the WTO dispute settlement mechanism: An analysis of eleven cases involving China's Accession Protocol. [PDF]

Heliyon
Qianyi S.
europepmc   +1 more source