This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Back home, beyond borders: a bioecological study of returnee public health scholars in a globalized health system. [PDF]
Ghimire A, Neupane MS.
europepmc +1 more source
The Application of EU Common Trade Policy in New Member States after Enlargement - Consequences on Russia's Trade with Poland [PDF]
When the Enlargement took place on 1 May 2004, The Common Trade Policy with all trade policy instrument were automatically applied to imports into the enlarged European Union.
Paulina Pospieszna
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Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
The Customs Union between Belarus, Kazakhstan and Russia: and Overview of Economic Implicaitons for Belarus [PDF]
The paper examines the economic implications of Belarus' participation in the newly created EURASEC Customs Union. The results of the calculations show that after the introduction of a common external tariff (CET) the level of tariff protection in ...
Irina Tochitskaya
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
JUCars-2024: A dataset of used car listings in Jordan. [PDF]
Thalji N, Tahat K.
europepmc +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
The issues and challenges of addressing the importation of unregistered pharmaceutical products in Malaysia. [PDF]
Lim LP, Bin Abdul Aziz MF.
europepmc +1 more source
Combating corruption at the customs administration [PDF]
Begovic, Boris, Mijatovic, Bosko et al.
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