Results 91 to 100 of about 276,549 (308)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Role of Innovation in the Development of Cross-Border Cooperation: Potential and Growth Guidance in the EAEU

open access: yesRUDN Journal of Economics
The focus of this research is the problem of insufficient elaboration of applied issues of world trade and international economic relations of neighboring countries.
Yury A. Tikhomirov
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Towards a Eurasian economic Union: the challenge of integration and unity [PDF]

open access: yes, 2012
otherwise – without the prior permission of ...
Blockmans, Steven   +2 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Sex, Reason, and a Taste for the Absurd [PDF]

open access: yes, 1993
Like much of Richard Posner\u27s best work, Sex and Reason does many things, and for that reason will no doubt attract a large and diverse readership.
West, Robin
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Features of the International e-Commerce Regulation in the EAEU Customs Legislation

open access: yesЕвразийская интеграция: экономика, право, политика, 2019
Features of the international e-commerce regulation in the EAEU customs legislation are regarded in the article. The EAEU members customs authorities have a deal with the necessity of accelerated registration of the goods flow in international mail, lack
A. S. Lebedev
doaj  

Concept for improving customs and tariff mechanisms for regulating international trade

open access: yesУправление
The purpose of the study is to develop main provisions of the concept of improving customs tariff mechanisms for regulating international trade.   As the subject of the study, the fundamental elements of the customs mechanisms development concept have ...
T. M. Vorotyntseva
doaj   +1 more source

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