Results 81 to 90 of about 2,275,229 (243)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

The role of the customs representative in the improvement of customs

open access: yesХабаршы. Заң сериясы, 2017
This article is devoted to the role and development of the Institute of customs representatives in the implementation of customs RK. Written by studying the publications of scientists, as well as its own scientific research examines some aspects of legal
Nuranova R. K.
doaj  

Principles of customs and tariff regulations in Ukraine

open access: yesEconomic scope, 2018
The article is devoted to the research about essence and principles of customs and tariff regulation in Ukraine. The current customs system, its functions, tasks and normative base are analyzed. Based on the analysis, a number of problems have to be solved in the near future, namely, the improvement of the regulatory and legislative framework for  the ...
Kakhovich, O. O., Prudius, A. V.
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

THE FISCAL- BUDGETARY IMPLICATIONS OF DETERMINING THE ORIGIN OF PRODUCTS [PDF]

open access: yes
The customs tariff for import is the main instrument for regulating the external commercial trade, according to the national economic benefits of the states. This practice in the international trade was ruled in Art.
Florin TUDOR
core  

Concept for improving customs and tariff mechanisms for regulating international trade

open access: yesУправление
The purpose of the study is to develop main provisions of the concept of improving customs tariff mechanisms for regulating international trade.   As the subject of the study, the fundamental elements of the customs mechanisms development concept have ...
T. M. Vorotyntseva
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Regional Trade Integration in East Africa: Trade and Revenue Impacts of the Planned East African Community Customs Union [PDF]

open access: yes
The paper provides empirical estimates for import and revenue implications that would follow implementation of the planned customs union between the East African Community member states Kenya, Tanzania, and Uganda. We use 2002 trade and trade policy data
Lucio Castro
core  

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