Results 51 to 60 of about 388,688 (309)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

The customs union is an important stage of the integrative cooperation development

open access: yesХабаршы. Заң сериясы, 2017
This article is about economic integration of Russia, Kazakhstan and Belarus and legal principles of the Union. Creating the Customs union between Kazakhstan, Belarus and Russia is an important stage of the integrative cooperation development ...
Andirzhanova G.A.
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Regional Trade Integration in East Africa: Trade and Revenue Impacts of the Planned East African Community Customs Union [PDF]

open access: yes
The paper provides empirical estimates for import and revenue implications that would follow implementation of the planned customs union between the East African Community member states Kenya, Tanzania, and Uganda. We use 2002 trade and trade policy data
Lucio Castro
core  

Таможенный союз нуждается в либерализации контроля таможенной стоимости [PDF]

open access: yes, 2010
THE CUSTOMS UNION REQUIRES CONTROL OF CUSTOMS COST LIBERALIZATION / ЦЫКУНОВ И.В., кандидат экономических наук, доцент; ГОЛОВКОВА Е.А., кандидат экономических наук, доцент (Белорусский государственный экономический университет, Минск).
Головкова, Е. А.   +1 more
core   +1 more source

The customs union argument for a monetary union [PDF]

open access: yes, 1990
If the real exchange rate follows approximately a random walk and in the presence of nontraded goods, a monetary union may generate a Pareto improvement. The argument is based on the analogy with the advantages that derive from the formation of a customs
Marrewijk, J.G.M. (Charles) van   +1 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Physical Persons as Participants in Customs Legal Relations within the Eurasian Economic Union

open access: yesМосковский журнал международного права, 2016
The article analyses legal foundations and variations of participation of physical persons in customs legal relations. It scrutinizes the law of the Eurasian Economic Union and the Russian Federation legislation on customs.
Sergey V. Khalipov
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Blockchain Technology as a Factor of Global Modernization of International Processes of Customs Regulation. Application of the Digital System of Distributed Registers in the Customs Union of the Eurasian Economic Union Countries

open access: yesУправленческое консультирование, 2018
The article is devoted to the application of blockchain technology in international customs regulation processes, as well as the application of this technology in the framework of modernization of customs administration processes in the zone of the ...
V. A. Shamakhov   +2 more
doaj   +1 more source

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