Results 61 to 70 of about 8,076 (266)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

EURASIAN CUSTOMS UNION – ANALYSES AND PERSPECTIVES [PDF]

open access: yesEURINT, 2014
In the era of Globalization the process of integration is speeded and taken to a different level. After the EU model, we are facing now with different entities trying to copy this model and adjusting it to their needs.
Brindusa-Nicoleta PINCU   +1 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Prospects of Enhancement of the Fulfilment Order of Customs Operations Connected with the Development of a Unified Automated Information System of Customs Bodies

open access: yesУправленческое консультирование, 2018
The speed of fulfilment of customs operations is one of the main criteria of the efficiency of customs bodies’ activity. Now the Government of the Russian Federation and the Federal Customs Service of Russia conduct systematic work directed on the ...
Aleksandr Sergeevich Abramov
doaj   +1 more source

The Customs Union

open access: yes, 2018
EU customs law has developed enormously since the entry into force of the Common Customs Tariff on 1 July 1968. The move away from issue-by-issue directives towards more generally applicable regulations heralded greater control at EU level over matters such as inward processing, ensuring more uniformity in the customs territory of the then Community ...
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Güney Kıbrıs’ın Gümrük Birliği’ne Katılım Sürecinde Karşılaşılan Sorunlar

open access: yesAnkara Avrupa Çalışmaları Dergisi, 2006
Ankara Agreement which was signed on the 12th of September 1963, and made Turkey an associate member to today's European Union, was based on a Customs Union between the parties and provided for the prospective full membership of Turkey to the European
S. Rıdvan Karluk
doaj  

The Zollverein and the Formation of a Customs Union [PDF]

open access: yes, 2010
The Zollverein, the German customs union of 1834, was the institutional centrepiece of Germany’s economic unification. A bargaining model is applied to analyze the structure of its negotiation process and accession sequence. The existence of negative coalition externalities, the effect of a coalition on non-participants, led Prussia to choose ...
openaire   +4 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

FİVE DECADES PLEDGE FOR TURKEY: ANKARA AGREEMENT AND BEYOND

open access: yesJournal of Smart Economic Growth, 2017
The Association Agreement between Turkey and the European Community set the goal of establishing a Customs Union between the Parties in a 3-stages process, with the hope of Turkey’s eventual membership to the European Economic Community. Despites Customs
Sibel MEHTER AYKIN, Ileana TACHE
doaj  

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