Results 51 to 60 of about 8,076 (266)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The customs union is an important stage of the integrative cooperation development

open access: yesХабаршы. Заң сериясы, 2017
This article is about economic integration of Russia, Kazakhstan and Belarus and legal principles of the Union. Creating the Customs union between Kazakhstan, Belarus and Russia is an important stage of the integrative cooperation development ...
Andirzhanova G.A.
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

ESTABLISHMENT OF CUSTOMS DUTIES IN THE EURASIAN ECONOMIC UNION

open access: yesФинансы: теория и практика, 2017
The paper deals with the relevant but underexplored issue of the customs law - the theoretical aspects of the customs duty establishment. The issue of customs duties is a subject of scientific interest due to their impact on the legal relations arising ...
V. A. Sbezhnev
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Physical Persons as Participants in Customs Legal Relations within the Eurasian Economic Union

open access: yesМосковский журнал международного права, 2016
The article analyses legal foundations and variations of participation of physical persons in customs legal relations. It scrutinizes the law of the Eurasian Economic Union and the Russian Federation legislation on customs.
Sergey V. Khalipov
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Effects of a Customs Union on Economic Growth: Empirical Evidence from Southern African Customs Union (SACU)

open access: yesЭкономика региона
This study analyses the effects of the Southern African Customs Union (SACU) on the economic growth of its member states based on unbalanced panel datasets.
Хансол Ли   +3 more
doaj   +1 more source

Blockchain Technology as a Factor of Global Modernization of International Processes of Customs Regulation. Application of the Digital System of Distributed Registers in the Customs Union of the Eurasian Economic Union Countries

open access: yesУправленческое консультирование, 2018
The article is devoted to the application of blockchain technology in international customs regulation processes, as well as the application of this technology in the framework of modernization of customs administration processes in the zone of the ...
V. A. Shamakhov   +2 more
doaj   +1 more source

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