Results 81 to 90 of about 388,688 (309)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Trade Effects of the East African Community [PDF]

open access: yes
This article evaluates the trade effects of the new East African Community, which fosters trade liberalisation among Kenya, Tanzania and Uganda. The analysis uses a disaggregated approach at the two-digit level of the Standard International Trade ...
Busse, Matthias, Shams, Rasul
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Turkey and Europe: Undivided but not united [PDF]

open access: yes
This article presents Turkey-Europe relations starting with the 19th century up to the present day with a view to understanding the developments that shaped current EU policies toward Turkey.
Erdogdu, Erkan
core   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

The Eurasian economic union and legal regulation of integration processes in the post-Soviet space

open access: yesХабаршы. Заң сериясы, 2018
Нe emergence and establishment of the Eurasian Economic Union, as well as the interaction of the integration process, which made possible the emergence of the Customs Union.
M.K. Nakysheva
doaj  

Sequencing Trade and Monetary Integration [PDF]

open access: yes
Regional integration for at least the last sixty years has focused on trade integration. Balassa’s canonical taxonomy of regional trading arrangements is often interpreted as a sequence from free trade area through customs union and common market to ...
Richard Pomfret
core  

Challenges and opportunities of the China – Gulf Cooperation Council Free Trade Agreement [PDF]

open access: yes, 2017
The free trade agreement between China and the Gulf Cooperation Council (“the GCC”) currently under negotiation is due to become China’s first comprehensive trade and investment agreement with a supranational customs union.
Villalta Puig, Gonzalo   +1 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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