Results 181 to 190 of about 6,230,123 (298)

Influence of cephalomedullary nail length and caput-collum-diaphyseal angle on tip-apex distance and early mechanical cut-out in trochanteric femur fractures. [PDF]

BMC Musculoskelet Disord
Philipp R, Kalb A, Notov D, Kleber C, Spiegl U.   +4 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Development of a novel prognostic assessment tool for recurrent respiratory papillomatosis. [PDF]

BMC Med
Yamada S, Ikegami T, Fukuhara T, Horichi Y, Shinomiya H, Nibu KI, Ebisumoto K, Iijima H, Sakai A, Okami K, Wasano K, Nakanishi Y, Yoshizaki T, Nakagawa T, Hanazawa T, Okamura J, Ueki Y, Horii A, Kise N, Suzuki M, Kasuga M, Yokota S, Takumi Y, Ishinaga H, Kitano M, Ota I, Masui T, Yoshimi N, Sasaki Y, Noda Y, Morita S, Takahashi G, Takeuchi K, Nakamura Y, Ishida K, Sugawara K, Matsuda S, Makoshi Y, Sugiyama N, Kano K, Sahara S, Kita J, Morita K, Mochizuki D, Nakanishi H, Imai A, Misawa Y, Takizawa Y, Kawasaki H, Misawa K.   +49 more
europepmc   +1 more source

PELANGGARAN KEAMANAN DAN KETERTIBAN NARAPIDANARNPADA LEMBAGA PEMASYARAKATAN KLAS IIA RNLHOKSEUMAWE [PDF]

, 2015
Cut Febriyanti
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Multicenter Assessment of Postoperative Mastocheck^® Dynamics Following Curative Breast Cancer Surgery. [PDF]

Cancers (Basel)
Shin H, Kim Y, Park JM, Yoon CS, Kim SS, Noh DY.   +5 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Uncoupling of the Helical Blade in a Proximal Femoral Nail - A Novel Mechanical Failure. [PDF]

J Orthop Case Rep
Bhakhar A, Kumar A, Sarkar B, Paul N, Yadav AK, Azam MQ.   +5 more
europepmc   +1 more source

HUBUNGAN PERILAKU PENGGUNAAN LENSA KONTAKRNDENGAN KEJADIAN INFEKSI MATA PADA MAHASISWARNFAKULTAS KEPERAWATAN UNIVERSITASRNSYIAH KUALA BANDA ACEH RNTAHUN 2015 [PDF]

, 2015
CUT IKLIMA
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source