Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
The New WHO Cut-off Point for Defining High-altitude Anemia may be Inadequate. [PDF]
Gonzales GF +7 more
europepmc +1 more source
Concordance and survival implications of preoperative subclassification of T3 rectal cancers by depth of mesorectal invasion using a 5-mm cut-off point with endorectal ultrasound and magnetic resonance imaging. [PDF]
García Botello S +7 more
europepmc +1 more source
cut vThigh rubbers cut off at ankles in spring time when tops become worn.DNE-cit -1974 WK JH 5/76Used I and SupUsed I3Not Usedcut off (the linnet/twine), cut out (a young seal), cut-tail, cut-throat(er), cut-off, cut pole, cutwater, cut tails, cut ...
core
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Determination of the Most Suitable Cut-Off Point of the Cervical Foraminal Cross-Sectional Area at the C5/6 Level to Predict Cervical Foraminal Bony Stenosis. [PDF]
Lee J +5 more
europepmc +1 more source
Can Tumour Volume Percentage in Radical Prostatectomy Predict Cancer Biochemical Recurrence? Determining a Cut-off Point and Composite Risk Factors Approach. [PDF]
Alenezi A, Ismail M, Eden C.
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The Optimal Cut-Off Point of Physical Activity for the Prevention of Childhood Overweight and Obesity. [PDF]
Wu S +5 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source

