Results 141 to 150 of about 823,385 (342)

Targeting Neutrophil/Eosinophil Extracellular Traps by Aptamer‐Functionalized Nanosheets to Overcome Recalcitrant Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
In this study, C‐TAH, as multifunctional nanosheets, is developed with tannic acid and histone aptamer coverage. C‐TAH displays mild cytotoxicity, robust dsDNA and NETs/EETs binding efficiency, and potent antioxidant and antibacterial ability in vitro. C‐TAH treatment ameliorates dysregulated inflammation and restores hearing function in animal models,
Yongqiang Xiao   +13 more
wiley   +1 more source

Lupus Vulgaris in a Maltese patient [PDF]

open access: yes, 2004
Introduction The incidence of cutaneous tuberculosis (TB) in the developed world has fallen, in parallel with the decline of other forms of TB. Nevertheless cases still occur and their diagnosis may be difficult.
Boffa, Michael J.   +2 more
core  

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

open access: yesAdvanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen   +17 more
wiley   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

open access: yesAdvanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen   +6 more
wiley   +1 more source

Advances in Medical Devices for Augmented Acupuncture Therapy

open access: yesAdvanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai   +7 more
wiley   +1 more source

Bionic Multimodal Augmented Somatosensory Receptor Enabled by Thermogalvanic Hydrogel

open access: yesAdvanced Science, EarlyView.
A skin‐inspired self‐powered multimodal fingertip receptor that integrates thermogalvanic hydrogels as active mechanoreceptors and thermoreceptors is proposed. By exploiting dynamic‐static thermovoltage of the hydrogel to visualize the unsteady interfacial heat conduction, different materials can be determined in 80 ms.
Ning Li   +6 more
wiley   +1 more source

Electrochemical CO2 Reduction on Janus Dual‐Atom Catalysts: Critical Role of Oxygen Coordination and an Effective Descriptor

open access: yesAdvanced Science, EarlyView.
Janus dual‐atom catalysts (DACs) with N3O3 hybrid coordination are designed with different combination of metal sites. Compared to normal DACs, most Janus DACs favor CH3OH or CH4 production over CO, driven by enhanced initial CO2 hydrogenation and stronger CO adsorption.
Hongling Liu   +5 more
wiley   +1 more source

Cutaneos larva migrans in travelers [PDF]

open access: yes, 1994
The symptoms, medical history, and treatment of 98 patients with cutaneous larva migrans (creeping eruption) who attended a travel-related-disease clinic during a period of 4 years are reviewed.
Jelinek, Thomas   +3 more
core  

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