Results 51 to 60 of about 1,185,716 (346)

A Novel 3D Culture Model of Human ASCs Reduces Cell Death in Spheroid Cores and Maintains Inner Cell Proliferation Compared With a Nonadherent 3D Culture

Frontiers in Cell and Developmental Biology, 2021
3D cell culture technologies have recently shown very valuable promise for applications in regenerative medicine, but the most common 3D culture methods for mesenchymal stem cells still have limitations for clinical application, mainly due to the ...
Liang Luo, Wei Zhang, Jing Wang, Ming Zhao, Kuo Shen, Yanhui Jia, Yan Li, Jian Zhang, Weixia Cai, Dan Xiao, Xiaozhi Bai, Kaituo Liu, Kejia Wang, Yue Zhang, Huayu Zhu, Qin Zhou, Dahai Hu   +16 more
doaj   +1 more source

Cutaneous adverse reaction during lithium treatment: a case report and updated systematic review with meta-analysis [PDF]

, 2017
OBJECTIVES: To present a new case of adverse cutaneous reaction during lithium treatment and to update the systematic review and meta-analysis of the incidence of this adverse reaction.
Manchia, Mirko, Minnai, Giampaolo, Pinna, Martina, Puddu, Sergio, Salis, Piergiorgio, Tondo, Leonardo   +5 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Exosomes derived from mouse vibrissa dermal papilla cells promote hair follicle regeneration during wound healing by activating Wnt/β-catenin signaling pathway

Journal of Nanobiotechnology
Hair follicle (HF) regeneration during wound healing continues to present a significant clinical challenge. Dermal papilla cell-derived exosomes (DPC-Exos) hold immense potential for inducing HF neogenesis.
Yage Shang, Mengyang Li, Lixia Zhang, Chao Han, Kuo Shen, Kejia Wang, Yan Li, Yue Zhang, Liang Luo, Yanhui Jia, Kai Guo, Weixia Cai, Jian Zhang, Xujie Wang, Hongtao Wang, Dahai Hu   +15 more
doaj   +1 more source

Increased Risk of Postoperative Complications in Patients with Hypertension Undergoing Mohs Micrographic Surgery

JID Innovations
Hypertension has been previously associated with higher intraoperative bleeding risk in patients undergoing Mohs micrographic surgery. However, the risks of common postoperative Mohs micrographic surgery complications have not been substantiated by large
Alexandra Elder, Henry Y. Yang, Megan O’Donnell-Cappelli, Jenna L. Mandel, Molly Wallace, Lauren Banner, Ramsay Hafer, Thomas Z. Rohan, Neda Nikbakht   +8 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Exosomes as novel biomarkers in sepsis and sepsis related organ failure

Journal of Translational Medicine
Sepsis, a severe and life-threatening condition arising from a dysfunctional host response to infection, presents considerable challenges to the health care system and is characterized by high mortality rates and substantial economic costs. Exosomes have
Yixuan Yuan, Yujie Xiao, Jiazhen Zhao, Lixia Zhang, Mengyang Li, Liang Luo, Yanhui Jia, Kejia Wang, Yuxi Chen, Peng Wang, Yuhang Wang, Jingtao Wei, Kuo Shen, Dahai Hu   +13 more
doaj   +1 more source

Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway

Stem cell research & therapeutics, 2020
Cutaneous wound healing represents a morphogenetic response to injury and is designed to restore anatomic and physiological function. Human bone marrow mesenchymal stem cell-derived exosomes (hBM-MSC-Ex) are a promising source for cell-free therapy and ...
Tiechao Jiang, Zhongyu Wang, Ji Sun
semanticscholar   +1 more source

An unusual case of intertrigo in an adult caused by purely cutaneous Langerhans cell histiocytosis [PDF]

, 2016
We report a case of persistent intertrigo in an adult, eventually diagnosed as cutaneous Langerhans cell histiocytosis (LCH). It is known that LCH has a predilection for intertriginous areas, however purely cutaneous disease as in our case, is uncommon ...
Baldacchino, Godfrey, Betts, Alexandra, Boffa, Michael J., Gatt, Alex   +3 more
core  

Optics-less smart sensors and a possible mechanism of cutaneous vision in nature

, 2008
Optics-less cutaneous (skin) vision is not rare among living organisms, though its mechanisms and capabilities have not been thoroughly investigated.
A. B. Sichert, A. H. G. R. Kan, D.-E. Nilsson, D.-E. Nilsson, E. Sampaio, G. Békésy Von, G. J. Molenaar, H. L. Van-Trees, H. P. Zavala, I. R. Schwab, J. Pettigrew, L. Yaroslavsky, L. Yaroslavsky, M. Gardner, M. M. Bongard, P. Bach-y-Rita, R. Parker, W. J. Gehring   +17 more
core   +1 more source