Results 111 to 120 of about 369,301 (296)

Validated LC‐MS/MS Method for Quantifying the Antiparasitic Nitroimidazole DNDI‐0690 in Preclinical Target Site PK/PD Studies

Biomedical Chromatography, Volume 39, Issue 8, August 2025.
ABSTRACT Understanding the target site pharmacokinetics (PK) of the nitroimidazole analog DNDI‐0690, a potential drug for the neglected parasitic disease leishmaniasis, is important due to the diversity of infected tissue sites and potential drug penetration variability.
Wietse M. Schouten, Katrien van Bocxlaer, Hilde Rosing, Alwin D. R. Huitema, Jos H. Beijnen, Jadel M. Kratz, Charles E. Mowbray, Thomas P. C. Dorlo   +7 more
wiley   +1 more source

Mini-Exon Genotyping of Leishmania Species in Khuzestan Province, Southwest Iran [PDF]

Iranian Journal of Parasitology, 2010
Background: Leishmaniasis is a protozoan disease cause by Leishmania genus. Anthroponotic and zoono­tic cutaneous leishmaniasis are endemic in Iran. The aim of this study was to identify the causative agent of cutaneous leishmaniasis by mini-exon gene in
J Saki, AR Meamar, H Oormazdi, L Akhlaghi, S Maraghi, M Mohebali, S Khademvatan, E Razmjou   +7 more
doaj   +1 more source

Cutaneous Leishmaniasis in Saudi Arabia: A Comprehensive Overview

Vector Borne and Zoonotic Diseases, 2017
Despite the great efforts by health authorities in Kingdom of Saudi Arabia (KSA), Cutaneous leishmaniasis (CL) continues to be a major public health problem in the country.
A. Abuzaid, Abdalmohsin M. Abdoon, Mohamed A. Aldahan, A. Alzahrani, R. F. Alhakeem, Abdullah M. Asiri, M. Alzahrani, Z. Memish   +7 more
semanticscholar   +1 more source

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone

Drug Development Research, Volume 86, Issue 5, August 2025.
ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp, Helena D. Janse van Rensburg, Simon S. Mnyakeni‐Moleele, Keisuke Suganuma, David D. N'Da   +4 more
wiley   +1 more source

New distributional data on sandflies from rubble walls in the Maltese Islands with an illustrated key to the Maltese species (Diptera: Phlebotominae) [PDF]

, 2009
The results of a survey which involved collecting phlebotomine sandflies in rubble walls from 20 different localities on the islands of Malta and Gozo in the period from August to October 2008 are reported. A total of 402 specimens were collected, all
Gatt, Paul, Mifsud, David, Williams, Josianne   +2 more
core  

Multiple Bilateral Erythematous and Suppurative Cutaneous Nodules in a 40‐Year‐Old Indian Female

JEADV Clinical Practice, EarlyView.
Aditi Anand, Shaivy Malik, Charanjeet Ahluwalia   +2 more
wiley   +1 more source

A Rare Periorbital Ulceronecrotic Wound: A Case of Anthrax Cellulitis

International Wound Journal, Volume 22, Issue 8, August 2025.
ABSTRACT Cutaneous anthrax is a zoonotic bacterial infection that mostly involves the head, neck, and upper extremities. Periorbital involvement of cutaneous anthrax is a rare presentation that can lead to severe irreversible complications. Herein, we describe a 2.5‐year‐old girl with periorbital anthrax cellulitis. She presented with a severe swelling
Monir Sadat Emadoleslami, Mohsen Pourazizi, Fereshte Rastegarnasab, Bahareh Abtahi‐Naeini, Niloofar Mohkamkar, Mohammad Allami   +5 more
wiley   +1 more source

Lupus Vulgaris on Face: A Case Report From Rural Nepal

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT Lupus vulgaris (LV), the most common form of cutaneous tuberculosis, results from Mycobacterium tuberculosis infection via hematogenous, lymphatic, or direct transmission in individuals with moderate immunity and high tuberculin sensitivity. It predominantly affects females, constituting 1%–2% of extrapulmonary tuberculosis cases, with facial ...
Sabin Kandel, Nikita Shah, Aayush Bist
wiley   +1 more source

A Declining Trend of 'Leishmaniasis' Based on Previous Data in Larstan, South of Iran 2007–2017

Annals of Global Health, 2019
Introduction: 'Cutaneous Leishmaniasis' is a unicellular of the Leishmania type, and 0.7 to 1.2 million people are annually infected by 'Cutaneous Leishmaniasis'. Larestan is one of the southern cities of Fars Province.
Ahmad Abolghazi, Forough Ebrahimizadeh, Fatemh Sharafi, Naser Hatami, Zahra Vafai   +4 more
doaj   +1 more source

Cutaneous Leishmaniasis and Conflict in Syria

Emerging Infectious Diseases, 2016
To the Editor: War, infection, and disease have always made intimate bedfellows, with disease recrudescence characterizing most conflict zones (1). Recently, increasing violence from civil war and terrorist activity in the Middle East has caused the ...
Waleed S. Al-Salem, D. Pigott, Krishanthi S Subramaniam, L. Haines, L. Kelly-Hope, D. Molyneux, Simon Iain Hay, Á. Acosta-Serrano   +7 more
semanticscholar   +1 more source